Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties.

Literature DB >> 18754727

Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties.

Maria Luiza Vilela Oliva¹, Uemura Misako Sampaio.

Abstract

Plant proteinase inhibitors are involved in the regulation of the activity of many proteinases and, in consequence, in biological processes driven by proteolysis. In this review, we summarize recent results on the activity of native Bauhinia inhibitors and synthetic derivatives. Structural and functional characteristics and the potential therapeutic use of these inhibitors are also discussed.

Entities: Gene

Mesh：

Substances：
Protease Inhibitors

Year: 2008 PMID： 18754727 DOI： 10.1515/BC.2008.119

Source DB: PubMed Journal: Biol Chem ISSN： 1431-6730 Impact factor: 3.915

Keyword Cloud
Cited

13 in total

1. Bauhinia bauhinioides cruzipain inhibitor reduces endothelial proliferation and induces an increase of the intracellular Ca2+ concentration.

Authors: Mehmet Bilgin; Christiane Neuhof; Oliver Doerr; Utz Benscheid; Sheila S Andrade; Astrid Most; Yaser Abdallah; Mariana Parahuleva; Dursun Guenduez; Maria L Oliva; Ali Erdogan
Journal: J Physiol Biochem Date: 2010-08-02 Impact factor: 4.158

2. A trypsin inhibitor from Sapindus saponaria L. seeds: purification, characterization, and activity towards pest insect digestive enzyme.

Authors: Maria Lígia R Macedo; Eduardo B S Diz Filho; Mariadas Graças M Freire; Maria Luiza V Oliva; Joana T Sumikawa; Marcos H Toyama; Sérgio Marangoni
Journal: Protein J Date: 2011-01 Impact factor: 2.371

3. Molecular characterization of a miraculin-like gene differentially expressed during coffee development and coffee leaf miner infestation.

Authors: Jorge Maurício Costa Mondego; Melina Pasini Duarte; Eduardo Kiyota; Leandro Martínez; Sandra Rodrigues de Camargo; Fernanda P De Caroli; Beatriz Santos Capela Alves; Sandra Maria Carmello Guerreiro; Maria Luiza Vilela Oliva; Oliveiro Guerreiro-Filho; Marcelo Menossi
Journal: Planta Date: 2010-10-08 Impact factor: 4.116

4. Effect of plant neutrophil elastase inhibitor on leucocyte migration, adhesion and cytokine release in inflammatory conditions.

Authors: C Oliveira; R A Navarro-Xavier; E A Anjos-Vallota; J O Martins; V L F Silveira; L R C Gonçalves; M S Araújo; G Motta; P Sannomiya; M L V Oliva
Journal: Br J Pharmacol Date: 2010-10 Impact factor: 8.739

5. Structure of BbKI, a disulfide-free plasma kallikrein inhibitor.

Authors: Dongwen Zhou; Daiane Hansen; Ivan G Shabalin; Alla Gustchina; Debora F Vieira; Marlon V de Brito; Ana Paula U Araújo; Maria Luiza V Oliva; Alexander Wlodawer
Journal: Acta Crystallogr F Struct Biol Commun Date: 2015-07-29 Impact factor: 1.056

6. The impaired viability of prostate cancer cell lines by the recombinant plant kallikrein inhibitor.

Authors: Joana Gasperazzo Ferreira; Paula Malloy Motta Diniz; Cláudia Alessandra Andrade de Paula; Yara Aparecida Lobo; Edgar Julian Paredes-Gamero; Thaysa Paschoalin; Amanda Nogueira-Pedro; Paloma Korehisa Maza; Marcos Sergio Toledo; Erika Suzuki; Maria Luiza Vilela Oliva
Journal: J Biol Chem Date: 2013-03-19 Impact factor: 5.157

Bauhinia Kunitz-type proteinase inhibitors: structural characteristics and biological properties.

1. Bauhinia bauhinioides cruzipain inhibitor reduces endothelial proliferation and induces an increase of the intracellular Ca2+ concentration.

2. A trypsin inhibitor from Sapindus saponaria L. seeds: purification, characterization, and activity towards pest insect digestive enzyme.

3. Molecular characterization of a miraculin-like gene differentially expressed during coffee development and coffee leaf miner infestation.

4. Effect of plant neutrophil elastase inhibitor on leucocyte migration, adhesion and cytokine release in inflammatory conditions.

5. Structure of BbKI, a disulfide-free plasma kallikrein inhibitor.

6. The impaired viability of prostate cancer cell lines by the recombinant plant kallikrein inhibitor.

7. Novel in vitro inhibitory functions of potato tuber proteinaceous inhibitors.

Review 8. Plant Protease Inhibitors in Therapeutics-Focus on Cancer Therapy.

9. Structural studies of complexes of kallikrein 4 with wild-type and mutated forms of the Kunitz-type inhibitor BbKI.

10. An Ethylene-Protected Achilles' Heel of Etiolated Seedlings for Arthropod Deterrence.