Literature DB >> 18752055

Triple test score for the evaluation of invasive ductal and lobular breast cancer.

Zsofia Egyed1, Balázs Járay, Janina Kulka, Zoltán Péntek.   

Abstract

The aim of our study was to compare the preoperative sum score diagnostics of invasive ductal and lobular cancers using three or four diagnostic methods. The novelty of this study is the examination of this phenomenon based on sum score, no such papers can be found in the literature. Ductal cancers have higher score values indicating easier diagnostics, but the difference in distribution of the scores was significant (p = 0.0086) only in case of the triple-test. The score values give appropriate opportunity to create their order of diagnostic power which was the same by both histologic types and in their subgroups with low sum-score: the strongest was cytology, followed by mammography, ultrasound and physical examination. No significant difference was found between the two histologic group in their mammographic appearances-stellate, circumscribed, assymmetric distortion or microcalcification-(p = 0.0694). In low score subgroup besides the occult forms, structural distortion and indeterminate microcalcifications overweighed the stellate and circumscribed lesions typical for the whole groups. In symptomless cases of both histologic groups only one strongly malignant diagnostic test result warrants the right diagnosis. Summarizing the score distribution of the results in case of four diagnostic tools the higher scores-indicating malignancy-were more frequent in the ductal group compared to the lobular ones. Extra attention has to be paid to rare radiomorphologic appearances and to the most deterministic examination, namely cytology.

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Year:  2008        PMID: 18752055     DOI: 10.1007/s12253-008-9083-3

Source DB:  PubMed          Journal:  Pathol Oncol Res        ISSN: 1219-4956            Impact factor:   3.201


  36 in total

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Journal:  JAMA       Date:  2003-03-19       Impact factor: 56.272

9.  Infiltrating lobular carcinoma of the breast. Clinicopathologic analysis of 975 cases with reference to data on conservative therapy and metastatic patterns.

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Journal:  Cancer       Date:  1996-01-01       Impact factor: 6.860

10.  Accuracy of breast cancer diagnosis by physical, radiologic and cytologic combined examinations.

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Journal:  Tumori       Date:  1983-04-30
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2.  Prognostic Significance of Substance P/Neurokinin 1 Receptor and Its Association with Hormonal Receptors in Breast Carcinoma.

Authors:  Riffat Mehboob; Syed Amir Gilani; Amber Hassan; Imrana Tanvir; Shaista Javaid; Sidra Khalid; Sana Hasan; Humaira Waseem; Ahmad Alwazzan; Miguel Munoz
Journal:  Biomed Res Int       Date:  2021-10-13       Impact factor: 3.411

  2 in total

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