Daniela Müller1, Günter Köhler, Ralf Ohlinger. 1. Department of Obstetrics and Gynaecology, Ernst-Moritz-Arndt University, Greifswald, Germany. dm022587@uni-greifswald.de
Abstract
BACKGROUND: In consideration of increasing incidence by introduction of screening mammography, the prevalence of distant metastases and necessity of staging procedures in early breast cancer should be proved. PATIENTS AND METHODS: A retrospective review was undertaken of 466 patients with newly diagnosed breast cancer in the period from 2003 to 2006. RESULTS: Distant metastases were found in 22 (4.8%) patients at the time of primary diagnosis of breast cancer. None of these patients had a tumour < or =1 cm and the percentage of metastatic disease increased with local extension (pT1 1.4%; pT2 7.9%; pT3 14.3%; pT4 23.1%; p<0.001) and nodal status (pN0 1.7%; pN1 3.8%; pN2 21.7%; pN3 17.6%; p<0.001) CONCLUSION: Indication for bone scan, liver ultrasound and chest x-ray should be limited to patients with tumours >2 cm, or tumours >1 cm with lymph node involvement (N1-3).
BACKGROUND: In consideration of increasing incidence by introduction of screening mammography, the prevalence of distant metastases and necessity of staging procedures in early breast cancer should be proved. PATIENTS AND METHODS: A retrospective review was undertaken of 466 patients with newly diagnosed breast cancer in the period from 2003 to 2006. RESULTS: Distant metastases were found in 22 (4.8%) patients at the time of primary diagnosis of breast cancer. None of these patients had a tumour < or =1 cm and the percentage of metastatic disease increased with local extension (pT1 1.4%; pT2 7.9%; pT3 14.3%; pT4 23.1%; p<0.001) and nodal status (pN0 1.7%; pN1 3.8%; pN2 21.7%; pN3 17.6%; p<0.001) CONCLUSION: Indication for bone scan, liver ultrasound and chest x-ray should be limited to patients with tumours >2 cm, or tumours >1 cm with lymph node involvement (N1-3).
Authors: Naoki Niikura; Colleen M Costelloe; John E Madewell; Naoki Hayashi; Tse-Kuan Yu; Jun Liu; Shana L Palla; Yutaka Tokuda; Richard L Theriault; Gabriel N Hortobagyi; Naoto T Ueno Journal: Oncologist Date: 2011-07-17
Authors: Sandeep Bhoriwal; S V S Deo; Rakesh Kumar; Sanjay Thulkar; Ajay Gogia; D N Sharma; Sandeep Mathur Journal: Indian J Surg Oncol Date: 2021-03-02
Authors: Salih Ozguven; Sabahat Inanir; Halil Turgut Turoglu; Tanju Yusuf Erdil; Mustafa Umit Ugurlu; Bahadir Gulluoglu Journal: Indian J Nucl Med Date: 2016 Jul-Sep