Literature DB >> 1874015

Recent studies on antimalarial efficacy of piperaquine and hydroxypiperaquine.

L Chen1.   

Abstract

Piperaquine and hydroxypiperaquine seem to be successful candidates of antimalarial drugs in China. Their antimalarial efficacy, experimental resistance, combination, mode of antimalarial action and clinical trials are described briefly.

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Year:  1991        PMID： 1874015

Source DB:  PubMed          Journal:  Chin Med J (Engl)        ISSN： 0366-6999            Impact factor:   2.628


  8 in total

Review 1.  Piperaquine: a resurgent antimalarial drug.

Authors:  Timothy M E Davis; Te-Yu Hung; Ing-Kye Sim; Harin A Karunajeewa; Kenneth F Ilett
Journal:  Drugs       Date:  2005       Impact factor: 9.546

2.  Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.

Authors:  Quinton L Fivelman; Ipemida S Adagu; David C Warhurst
Journal:  Antimicrob Agents Chemother       Date:  2007-04-02       Impact factor: 5.191

3.  Effects of a high-fat meal on the relative oral bioavailability of piperaquine.

Authors:  Ing-Kye Sim; Timothy M E Davis; Kenneth F Ilett
Journal:  Antimicrob Agents Chemother       Date:  2005-06       Impact factor: 5.191

4.  Pharmacokinetics and pharmacodynamics of piperaquine in a murine malaria model.

Authors:  Brioni R Moore; Kevin T Batty; Christopher Andrzejewski; Jeffrey D Jago; Madhu Page-Sharp; Kenneth F Ilett
Journal:  Antimicrob Agents Chemother       Date:  2007-11-05       Impact factor: 5.191

5.  Population pharmacokinetics of piperaquine in adults and children with uncomplicated falciparum or vivax malaria.

Authors:  Te-Yu Hung; Timothy M E Davis; Kenneth F Ilett; Harin Karunajeewa; Sean Hewitt; Mey Bouth Denis; Chiv Lim; Doung Socheat
Journal:  Br J Clin Pharmacol       Date:  2004-03       Impact factor: 4.335

6.  In vitro activities of piperaquine and other 4-aminoquinolines against clinical isolates of Plasmodium falciparum in Cameroon.

Authors:  Leonardo K Basco; Pascal Ringwald
Journal:  Antimicrob Agents Chemother       Date:  2003-04       Impact factor: 5.191

7.  Efficacy and Safety of Fosmidomycin-Piperaquine as Nonartemisinin-Based Combination Therapy for Uncomplicated Falciparum Malaria: A Single-Arm, Age De-escalation Proof-of-Concept Study in Gabon.

Authors:  Ghyslain Mombo-Ngoma; Jonathan Remppis; Moritz Sievers; Rella Zoleko Manego; Lilian Endamne; Lumeka Kabwende; Luzia Veletzky; The Trong Nguyen; Mirjam Groger; Felix Lötsch; Johannes Mischlinger; Lena Flohr; Johanna Kim; Chiara Cattaneo; David Hutchinson; Stephan Duparc; Joerg Moehrle; Thirumalaisamy P Velavan; Bertrand Lell; Michael Ramharter; Ayola Akim Adegnika; Benjamin Mordmüller; Peter G Kremsner
Journal:  Clin Infect Dis       Date:  2018-06-01       Impact factor: 9.079

Review 8.  Prospects for the treatment of drug-resistant malaria parasites.

Authors:  Leann Tilley; Timothy M E Davis; Patrick G Bray
Journal:  Future Microbiol       Date:  2006-06       Impact factor: 3.165
  8 in total

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