Literature DB >> 17404003

Effects of piperaquine, chloroquine, and amodiaquine on drug uptake and of these in combination with dihydroartemisinin against drug-sensitive and -resistant Plasmodium falciparum strains.

Quinton L Fivelman1, Ipemida S Adagu, David C Warhurst.   

Abstract

Piperaquine is being developed as a long-acting component in artemisinin combination therapies. It was highly active in vitro and drug interaction studies showed that dihydroartemisinin combinations with piperaquine, chloroquine, and amodiaquine were indifferent tending toward antagonism. Competitive uptake of radiolabeled chloroquine and dihydroartemisinin in combination with other antimalarials was observed.

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Year:  2007        PMID： 17404003      PMCID： PMC1891407          DOI： 10.1128/AAC.01479-06

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  21 in total

1.  Averting a malaria disaster.

Authors:  N J White; F Nosten; S Looareesuwan; W M Watkins; K Marsh; R W Snow; G Kokwaro; J Ouma; T T Hien; M E Molyneux; T E Taylor; C I Newbold; T K Ruebush; M Danis; B M Greenwood; R M Anderson; P Olliaro
Journal:  Lancet       Date:  1999-06-05       Impact factor: 79.321

2.  Access to hematin: the basis of chloroquine resistance.

Authors:  P G Bray; M Mungthin; R G Ridley; S A Ward
Journal:  Mol Pharmacol       Date:  1998-07       Impact factor: 4.436

3.  Antagonism of chloroquine with other antimalarials.

Authors:  E Stahel; P Druilhe; M Gentilini
Journal:  Trans R Soc Trop Med Hyg       Date:  1988       Impact factor: 2.184

4.  Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites.

Authors:  A C Chou; R Chevli; C D Fitch
Journal:  Biochemistry       Date:  1980-04-15       Impact factor: 3.162

5.  Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance.

Authors:  F Verdier; J Le Bras; F Clavier; I Hatin; M C Blayo
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

6.  The interaction of artemisinin with malarial hemozoin.

Authors:  Y L Hong; Y Z Yang; S R Meshnick
Journal:  Mol Biochem Parasitol       Date:  1994-01       Impact factor: 1.759

7.  Molecular modeling studies of the artemisinin (qinghaosu)-hemin interaction: docking between the antimalarial agent and its putative receptor.

Authors:  K L Shukla; T M Gund; S R Meshnick
Journal:  J Mol Graph       Date:  1995-08

8.  Artemisinin (qinghaosu): the role of intracellular hemin in its mechanism of antimalarial action.

Authors:  S R Meshnick; A Thomas; A Ranz; C M Xu; H Z Pan
Journal:  Mol Biochem Parasitol       Date:  1991-12       Impact factor: 1.759

9.  Recent studies on antimalarial efficacy of piperaquine and hydroxypiperaquine.

Authors:  L Chen
Journal:  Chin Med J (Engl)       Date:  1991-02       Impact factor: 2.628

10.  Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity in Plasmodium falciparum.

Authors:  P G Bray; O Janneh; K J Raynes; M Mungthin; H Ginsburg; S A Ward
Journal:  J Cell Biol       Date:  1999-04-19       Impact factor: 10.539
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  12 in total

1.  Absence of association between piperaquine in vitro responses and polymorphisms in the pfcrt, pfmdr1, pfmrp, and pfnhe genes in Plasmodium falciparum.

Authors:  Sébastien Briolant; Maud Henry; Claude Oeuvray; Rémy Amalvict; Eric Baret; Eric Didillon; Christophe Rogier; Bruno Pradines
Journal:  Antimicrob Agents Chemother       Date:  2010-06-14       Impact factor: 5.191

Review 2.  Dihydroartemisinin/Piperaquine: a review of its use in the treatment of uncomplicated Plasmodium falciparum malaria.

Authors:  Gillian M Keating
Journal:  Drugs       Date:  2012-05-07       Impact factor: 9.546

3.  Role of known molecular markers of resistance in the antimalarial potency of piperaquine and dihydroartemisinin in vitro.

Authors:  Sant Muangnoicharoen; David J Johnson; Sornchai Looareesuwan; Srivicha Krudsood; Stephen A Ward
Journal:  Antimicrob Agents Chemother       Date:  2009-02-02       Impact factor: 5.191

4.  In vitro sensitivities of Plasmodium falciparum isolates from the China-Myanmar border to piperaquine and association with polymorphisms in candidate genes.

Authors:  Mingming Hao; Dandan Jia; Qing Li; Yongshu He; Lili Yuan; Shuhui Xu; Kexuan Chen; Jia Wu; Lijuan Shen; Lin Sun; Hongbin Zhao; Zhaoqing Yang; Liwang Cui
Journal:  Antimicrob Agents Chemother       Date:  2013-01-28       Impact factor: 5.191

5.  Pharmacokinetics and ex vivo pharmacodynamic antimalarial activity of dihydroartemisinin-piperaquine in patients with uncomplicated falciparum malaria in Vietnam.

Authors:  Dao Van Hoang Nguyen; Quoc Phuc Nguyen; Ngoa Dang Nguyen; Thuy Thi Thanh Le; The Duy Nguyen; Duy Ngoc Dinh; Thanh Xuan Nguyen; Dai Bui; Marina Chavchich; Michael D Edstein
Journal:  Antimicrob Agents Chemother       Date:  2009-06-15       Impact factor: 5.191

6.  Initiation of gametocytogenesis at very low parasite density in Plasmodium falciparum infection.

Authors:  Ryan Farid; Matthew W Dixon; Leann Tilley; James S McCarthy
Journal:  J Infect Dis       Date:  2017-04-01       Impact factor: 5.226

7.  Investigating antimalarial drug interactions of emetine dihydrochloride hydrate using CalcuSyn-based interactivity calculations.

Authors:  Holly Matthews; Jon Deakin; May Rajab; Maryam Idris-Usman; Niroshini J Nirmalan
Journal:  PLoS One       Date:  2017-03-03       Impact factor: 3.240

8.  Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum.

Authors:  Aurélie Pascual; Philippe Parola; Françoise Benoit-Vical; Fabrice Simon; Denis Malvy; Stéphane Picot; Pascal Delaunay; Didier Basset; Danièle Maubon; Bernard Faugère; Guillaume Ménard; Nathalie Bourgeois; Claude Oeuvray; Eric Didillon; Christophe Rogier; Bruno Pradines
Journal:  Malar J       Date:  2012-02-14       Impact factor: 2.979

9.  Plasmodium vivax trophozoites insensitive to chloroquine.

Authors:  Wesley W Sharrock; Rossarin Suwanarusk; Usa Lek-Uthai; Michael D Edstein; Varakorn Kosaisavee; Thomas Travers; Anchalee Jaidee; Kanlaya Sriprawat; Ric N Price; François Nosten; Bruce Russell
Journal:  Malar J       Date:  2008-05-27       Impact factor: 2.979

Review 10.  Pharmacological considerations in the design of anti-malarial drug combination therapies - is matching half-lives enough?

Authors:  Ian M Hastings; Eva Maria Hodel
Journal:  Malar J       Date:  2014-02-20       Impact factor: 2.979
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