BACKGROUND: The aim of this study was to evaluate the feasibility and the accuracy of sentinel lymph node biopsy in multicentric breast cancer (MBC) performed by means of a subareolar (SA) injection of both 99Tc-labeled human albumin colloid and lymphazurin. METHODS: Between January 2002 and October 2007, 34 patients with MBC with clinically negative axilla underwent sentinel lymph node biopsy (SLNB) followed by total axillary node dissection (AD). Overall successful identification rate of SLN was 100%; there were no false negatives and overall accuracy rate was 100%. RESULTS: The mean number of sentinel lymph nodes (SLNs) identified was 1.8 +/- 0.88 (range = 1-4); the mean number of axillary lymph nodes examined was 21.4 +/- 5.76 (range = 8-36). CONCLUSIONS: The authors conclude that SA injection of the tracer is feasible and efficacious in the identification of the SLN. The accuracy of SLNB in MBC is comparable to that obtained in unifocal disease.
BACKGROUND: The aim of this study was to evaluate the feasibility and the accuracy of sentinel lymph node biopsy in multicentric breast cancer (MBC) performed by means of a subareolar (SA) injection of both 99Tc-labeled human albumin colloid and lymphazurin. METHODS: Between January 2002 and October 2007, 34 patients with MBC with clinically negative axilla underwent sentinel lymph node biopsy (SLNB) followed by total axillary node dissection (AD). Overall successful identification rate of SLN was 100%; there were no false negatives and overall accuracy rate was 100%. RESULTS: The mean number of sentinel lymph nodes (SLNs) identified was 1.8 +/- 0.88 (range = 1-4); the mean number of axillary lymph nodes examined was 21.4 +/- 5.76 (range = 8-36). CONCLUSIONS: The authors conclude that SA injection of the tracer is feasible and efficacious in the identification of the SLN. The accuracy of SLNB in MBC is comparable to that obtained in unifocal disease.
Authors: Todd M Tuttle; Marybeth Colbert; Robert Christensen; Kevin J Ose; Thomas Jones; Robert Wetherille; Joel Friedman; Karen Swenson; Kelly M McMasters Journal: Ann Surg Oncol Date: 2002 Jan-Feb Impact factor: 5.344
Authors: Aleodor A Andea; Tracie Wallis; Lisa A Newman; David Bouwman; Jyotirmoy Dey; Daniel W Visscher Journal: Cancer Date: 2002-03-01 Impact factor: 6.860
Authors: Giovanni D'Eredita'; Carmela Giardina; Giuseppe Ingravallo; Giuseppe Rubini; Vincenzo Lattanzio; Tommaso Berardi Journal: Breast Date: 2007-02-09 Impact factor: 4.380
Authors: Eleni Tousimis; Kimberly J Van Zee; Jane V Fey; Laura Weldon Hoque; Lee K Tan; Hiram S Cody; Patrick I Borgen; Leslie L Montgomery Journal: J Am Coll Surg Date: 2003-10 Impact factor: 6.113