Literature DB >> 11768675

Lymphoscintigraphic anatomy of sentinel lymphatic channels after subareolar injection of Technetium 99m sulfur colloid.

K A Kern1.   

Abstract

BACKGROUND: Injection of Technetium 99m sulfur colloid (Tc-99m-SC) into the subareolar lymphatic plexus provides a rapid and reliable method of identifying breast sentinel lymph nodes and their lymphatic connections to the areola, termed sentinel lymphatic channels (SLCs). The objective of this study was to define the anatomic origin, number, and direction of the SLC in relation to the areola after subareolar injection of Tc-99m-SC. STUDY
DESIGN: Using a hand-held goniometer, the exit angle (theta(e)) and direction from the vertical (to the patient's right or left) of SLCs were determined in 87 successful preoperative lymphoscintigrams (46 left breast and 41 right breast).
RESULTS: One major lymphatic trunk was identified in 91% of cases (n = 79), and two lymphatic trunks were identified in 9% of cases (n = 8). Overall, 24% (n = 21) of major lymphatic trunks exited the areola vertically (theta(e) = 0 degrees), 33% (n = 29) exited the areola with theta(e) = right or left 1 to 30 degrees, and 32% (n = 28) exited with a theta(e) = right or left 31 to 60 degrees. In total, 90% (n = 78) of SLCs exited the areola with a theta(e) = right or left 0 to 60 degrees, equivalent to 10 to 12 o'clock in the right breast, and 12 to 2 o'clock in the left breast.
CONCLUSIONS: Radial angular measurements of SLCs from preoperative lymphoscintigrams performed by SA injection confirm that the origin of the majority of SLCs is within the upper, outer edge of the areola, and that all SLCs ultimatelytraverse the upper, outer quadrant of the breast and terminate on axillary sentinel nodes.

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Year:  2001        PMID: 11768675     DOI: 10.1016/s1072-7515(01)01068-7

Source DB:  PubMed          Journal:  J Am Coll Surg        ISSN: 1072-7515            Impact factor:   6.113


  12 in total

1.  Results of preoperative lymphoscintigraphy for breast cancer are predictive of identification of axillary sentinel lymph nodes.

Authors:  Frédéric Marchal; Philippe Rauch; Olivier Morel; Jean Claude Mayer; Pierre Olivier; Agnès Leroux; Jean Luc Verhaeghe; François Guillemin
Journal:  World J Surg       Date:  2006-01       Impact factor: 3.352

2.  Clinicopathologic factors associated with false-negative sentinel lymph-node biopsy in breast cancer.

Authors:  Robert C G Martin; Anees Chagpar; Charles R Scoggins; Michael J Edwards; Lee Hagendoorn; Arnold J Stromberg; Kelly M McMasters
Journal:  Ann Surg       Date:  2005-06       Impact factor: 12.969

3.  Subareolar subcutaneous injection of blue dye versus peritumoral injection of technetium-labeled human albumin to identify sentinel lymph nodes in breast cancer patients.

Authors:  Roland Reitsamer; Florentia Peintinger; Lukas Rettenbacher; Eva Prokop; Felix Sedlmayer
Journal:  World J Surg       Date:  2003-10-28       Impact factor: 3.352

4.  The accuracy of sentinel lymph node biopsy in the treatment of multicentric invasive breast cancer using a subareolar injection of tracer.

Authors:  Calogero Cipolla; Salvatore Vieni; Salvatore Fricano; Daniela Cabibi; Giuseppa Graceffa; Renato Costa; Stefania Latteri; Mario A Latteri
Journal:  World J Surg       Date:  2008-11       Impact factor: 3.352

5.  Lymphoscintigraphy and triangulated body marking for morbidity reduction during sentinel node biopsy in breast cancer.

Authors:  Borys R Krynyckyi; Michail K Shafir; Suk Chul Kim; Dong Wook Kim; Arlene Travis; Renee M Moadel; Chun K Kim
Journal:  Int Semin Surg Oncol       Date:  2005-11-08

6.  Multifocality and multicentricity are not contraindications for sentinel lymph node biopsy in breast cancer surgery.

Authors:  Alberta Ferrari; Paolo Dionigi; Francesca Rovera; Luigi Boni; Giorgio Limonta; Silvana Garancini; Diego De Palma; Gianlorenzo Dionigi; Cristiana Vanoli; Mario Diurni; Giulio Carcano; Renzo Dionigi
Journal:  World J Surg Oncol       Date:  2006-11-20       Impact factor: 2.754

7.  The sentinel node in breast cancer: an update.

Authors:  Conor D Collins
Journal:  Cancer Imaging       Date:  2005-11-23       Impact factor: 3.909

8.  A novel finding of sentinel lymphatic channels in early stage breast cancer patients: which may influence detection rate and false-negative rate of sentinel lymph node biopsy.

Authors:  Minghai Wang; Wenbin Zhou; Yingchun Zhao; Tiansong Xia; Xiaoming Zha; Qiang Ding; Xiaoan Liu; Yi Zhao; Lijun Ling; Lin Chen; Shui Wang
Journal:  PLoS One       Date:  2012-12-04       Impact factor: 3.240

9.  Current status of sentinel lymph node biopsy in solid malignancies.

Authors:  Amit Goyal; Robert E Mansel
Journal:  World J Surg Oncol       Date:  2004-04-24       Impact factor: 2.754

Review 10.  The sentinel node in breast cancer.

Authors:  Conor D Collins
Journal:  Cancer Imaging       Date:  2008-10-04       Impact factor: 3.909

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