BACKGROUND AND AIMS: The 5-year incidence of cardiovascular disease (CVD) in relation to dietary habits, among men and women from Greece, was evaluated. METHODS AND RESULTS: From May 2001 to December 2002, 1514 men and 1528 women (>18 years) without any clinical evidence of CVD, living in the Attica area, Greece, were enrolled in the ATTICA study. In 2006, a group of experts performed the 5-year follow-up (941 of the 3042 participants were lost). Development of CVD (coronary heart disease, acute coronary syndromes, stroke, or other CVD) during the follow-up period was defined according to WHO ICD-10 criteria. Principal components analysis was applied, and 15 dietary patterns were extracted (71% of total information explained) from 26 foods or food groups. The 5-year incidence of CVD was 11.0% in men and 6.1% in women (p<0.001); the case fatality rate was 1.6%. Multi-adjusted analysis revealed that the dietary pattern that was mainly characterized by cereals, small fish, hardtack and olive oil intake, was associated with lower CVD risk (HR per 1 unit=0.72, 95% CI 0.52-1.00); the pattern that was characterized by fruits, vegetables intake and olive oil use in daily cooking was associated with lower CVD risk (HR per 1 unit=0.80, 95% CI 0.66-0.97); while patterns that were mainly characterized by sweets, red meat, margarine, salty nuts intake, and hard cheese, as well as alcohol intake, were associated with higher CVD risk (HR per 1 unit=1.26, 95% CI 1.01-1.56, and HR per 1 unit=1.32, 95% CI 1.05-1.66, respectively). CONCLUSIONS: Multivariate statistical methods revealed dietary patterns based on empirical epidemiological data which were associated with the development of CVD.
BACKGROUND AND AIMS: The 5-year incidence of cardiovascular disease (CVD) in relation to dietary habits, among men and women from Greece, was evaluated. METHODS AND RESULTS: From May 2001 to December 2002, 1514 men and 1528 women (>18 years) without any clinical evidence of CVD, living in the Attica area, Greece, were enrolled in the ATTICA study. In 2006, a group of experts performed the 5-year follow-up (941 of the 3042 participants were lost). Development of CVD (coronary heart disease, acute coronary syndromes, stroke, or other CVD) during the follow-up period was defined according to WHO ICD-10 criteria. Principal components analysis was applied, and 15 dietary patterns were extracted (71% of total information explained) from 26 foods or food groups. The 5-year incidence of CVD was 11.0% in men and 6.1% in women (p<0.001); the case fatality rate was 1.6%. Multi-adjusted analysis revealed that the dietary pattern that was mainly characterized by cereals, small fish, hardtack and olive oil intake, was associated with lower CVD risk (HR per 1 unit=0.72, 95% CI 0.52-1.00); the pattern that was characterized by fruits, vegetables intake and olive oil use in daily cooking was associated with lower CVD risk (HR per 1 unit=0.80, 95% CI 0.66-0.97); while patterns that were mainly characterized by sweets, red meat, margarine, salty nuts intake, and hard cheese, as well as alcohol intake, were associated with higher CVD risk (HR per 1 unit=1.26, 95% CI 1.01-1.56, and HR per 1 unit=1.32, 95% CI 1.05-1.66, respectively). CONCLUSIONS: Multivariate statistical methods revealed dietary patterns based on empirical epidemiological data which were associated with the development of CVD.
Authors: Jennifer A Nettleton; Nena Matijevic; Jack L Follis; Aaron R Folsom; Eric Boerwinkle Journal: Atherosclerosis Date: 2010-04-29 Impact factor: 5.162
Authors: Dalia Ieva Luksiene; Migle Baceviciene; Abdonas Tamosiunas; Evelina Daugeliene; Daina Kranciukaite Journal: Int J Public Health Date: 2010-08-12 Impact factor: 3.380
Authors: Sabita S Soedamah-Muthu; Eric L Ding; Wael K Al-Delaimy; Frank B Hu; Marielle F Engberink; Walter C Willett; Johanna M Geleijnse Journal: Am J Clin Nutr Date: 2010-11-10 Impact factor: 7.045
Authors: Cécilia Samieri; Qi Sun; Mary K Townsend; Stephanie E Chiuve; Olivia I Okereke; Walter C Willett; Meir Stampfer; Francine Grodstein Journal: Ann Intern Med Date: 2013-11-05 Impact factor: 25.391