Literature DB >> 18720052

Dental status and oral function in an adult group of subjects with thalidomide embryopathy - a clinical and questionnaire study.

Anders Ekfeldt1, Gunnar E Carlsson.   

Abstract

OBJECTIVE: The purpose of the study was to present the results of an oral examination of individuals with thalidomide embryopathy in relation to dental conditions and functional aspects of the masticatory system, with a special focus on tooth wear.
MATERIAL AND METHODS: All 108 subjects with thalidomide embryopathy living in Sweden were invited to participate in a comprehensive investigation, and approximately one-third, 31 subjects (13 F and 18 M, aged 45-49 years), took part. The methods included a questionnaire and clinical and radiographic examinations.
RESULTS: Most of the subjects had regular dental care, which they in general considered sufficient. All except one always brushed their teeth themselves. One subject had limited mouth opening (25 mm). There were no great deviations from normal anatomy and function of the masticatory system. Caries and periodontal conditions were also normal. Regurgitation was reported by 42% of the subjects. Tooth wear was more extensive than in comparable age groups. About a third of the subjects had Class III or edge-to-edge occlusion.
CONCLUSIONS: In general, subjects with thalidomide embryopathy had no great deviations in dental conditions from people of the same age in the general population except for an increased rate of tooth wear and a higher prevalence of prenormal jaw relations. Tooth wear was related less to use of the teeth as tools and more to dental erosion associated, among other things, with a high rate of regurgitation.

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Year:  2008        PMID: 18720052     DOI: 10.1080/00016350802307638

Source DB:  PubMed          Journal:  Acta Odontol Scand        ISSN: 0001-6357            Impact factor:   2.331


  5 in total

1.  Long-term follow-up of thalidomide embryopathy: malformations and development of osteoarthritis in the lower extremities and evaluation of upper extremity function.

Authors:  Shadi A Ghassemi Jahani; Barbro Danielson; Jón Karlsson; Aina J Danielsson
Journal:  J Child Orthop       Date:  2014-10-10       Impact factor: 1.548

2.  Degenerative Changes in the Cervical Spine Are More Common in Middle-Aged Individuals with Thalidomide Embryopathy than in Healthy Controls.

Authors:  Shadi A Ghassemi Jahani; Aina Danielsson; Rana Ab-Fawaz; Hanna Hebelka; Barbro Danielson; Helena Brisby
Journal:  PLoS One       Date:  2016-05-13       Impact factor: 3.240

3.  Health-related quality of life and function in middle-aged individuals with thalidomide embryopathy.

Authors:  Shadi A Ghassemi Jahani; Jon Karlsson; Helena Brisby; Aina J Danielsson
Journal:  J Child Orthop       Date:  2016-11-16       Impact factor: 1.548

4.  The health and quality of life of Thalidomide survivors as they age - Evidence from a UK survey.

Authors:  Elizabeth Newbronner; Caroline Glendinning; Karl Atkin; Ruth Wadman
Journal:  PLoS One       Date:  2019-01-16       Impact factor: 3.240

5.  Middle-aged individuals with thalidomide embryopathy have undergone few surgical limb procedures and demonstrate a high degree of physical independence.

Authors:  Shadi A Ghassemi Jahani; Aina Danielsson; Jon Karlsson; Helena Brisby
Journal:  PLoS One       Date:  2017-10-20       Impact factor: 3.240

  5 in total

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