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Literature DB >> 187150

Comparison of the humoral and cellular immune response after immunization with live, UV inactivated herpes simplex virus and a subunit vaccine and efficacy of these immunizations.

Abstract

Antibody and cell-mediated immune responses were measured in rabbits immunized with live, UV inactivated herpes simplex virus or with a subunit vaccine containing envelope proteins. All the types of immunization procedures induced the production of antibody as well as a specific cellular immunity. Furthermore, the subunit vaccine was as effective as the immunization with live or UV inactivated virus to prevent death upon challenge with live HSV. Live HSV induced a transient unresponsiveness of both B and T cells to in vitro stimulation with various mitogens.

Entities: Disease Species

Mesh：

Substances：

Year: 1976 PMID： 187150 DOI： 10.1007/bf01317862

Source DB: PubMed Journal: Arch Virol ISSN： 0304-8608 Impact factor: 2.574

19 in total

1. Cell mediated immunity in experimental rubella infections.

Authors: R Cappel
Journal: Arch Virol Date: 1975 Impact factor: 2.574

2. The Epstein-Barr virus and neoplasia.

Authors: G Klein
Journal: N Engl J Med Date: 1975-12-25 Impact factor: 91.245

3. Inhibition of the mitogenic response of normal peripheral lymphocytes by extracts or supernatant fluids of a Herpesvirus saimiri lymphoid tumor cell line.

Authors: R H Neubauer; W C Wallen; H Rabin
Journal: Infect Immun Date: 1975-11 Impact factor: 3.441

4. Efficacy and immune response to rubella subunits vaccines.

Authors: R Cappel; F De Cuyper
Journal: Arch Virol Date: 1976 Impact factor: 2.574

Review 5. The causative role of herpesvirus type 2 in cervical cancer.

Authors: J L Melnick; E Adam; W E Rawls
Journal: Cancer Date: 1974-10 Impact factor: 6.860

6. Transformation of cultured mammalian cells by viable herpes simplex virus subtypes 1 and 2.

Authors: B Garfinkle; B R McAuslan
Journal: Proc Natl Acad Sci U S A Date: 1974-01 Impact factor: 11.205

7. Cytomegalovirus-induced immune suppression. II. Cell-mediated immunity.

Authors: R J Howard; J Miller; J S Najarian
Journal: Clin Exp Immunol Date: 1974-09 Impact factor: 4.330

8. Onocogenic conversion of normal cells by inactivated herpes simplex viruses.

Authors: F Rapp; R Duff
Journal: Cancer Date: 1974-10 Impact factor: 6.860

9. Letter: Viral-antibody detection by a more sensitive complement-fixation reaction.

Authors: G Zissis; G Clinet
Journal: Lancet Date: 1974-04-20 Impact factor: 79.321

10. A micro-mixed leukocyte culture technique using whole blood.

Authors: G D Stockman; D M Mumford; J R Wilbur
Journal: Int Arch Allergy Appl Immunol Date: 1972

16 in total

1. Protective effect of an oral infection with herpes simplex virus type 1 against subsequent genital infection with herpes simplex virus type 2.

Authors: B Sturn; K E Schneweis
Journal: Med Microbiol Immunol Date: 1978-07-04 Impact factor: 3.402

2. Vaccination for herpes simplex genitalis.

Authors: T Nasemann; S W Wassilew
Journal: Br J Vener Dis Date: 1979-04

3. Immune responses in mice against herpes simplex virus: mechanisms of protection against facial and ganglionic infections.

Authors: H J Zweerink; D Martinez; R J Lynch; L W Stanton
Journal: Infect Immun Date: 1981-01 Impact factor: 3.441

Comparison of the humoral and cellular immune response after immunization with live, UV inactivated herpes simplex virus and a subunit vaccine and efficacy of these immunizations.

1. Cell mediated immunity in experimental rubella infections.

2. The Epstein-Barr virus and neoplasia.

3. Inhibition of the mitogenic response of normal peripheral lymphocytes by extracts or supernatant fluids of a Herpesvirus saimiri lymphoid tumor cell line.

4. Efficacy and immune response to rubella subunits vaccines.

Review 5. The causative role of herpesvirus type 2 in cervical cancer.

6. Transformation of cultured mammalian cells by viable herpes simplex virus subtypes 1 and 2.

7. Cytomegalovirus-induced immune suppression. II. Cell-mediated immunity.

8. Onocogenic conversion of normal cells by inactivated herpes simplex viruses.

9. Letter: Viral-antibody detection by a more sensitive complement-fixation reaction.

10. A micro-mixed leukocyte culture technique using whole blood.

1. Protective effect of an oral infection with herpes simplex virus type 1 against subsequent genital infection with herpes simplex virus type 2.

2. Vaccination for herpes simplex genitalis.

3. Immune responses in mice against herpes simplex virus: mechanisms of protection against facial and ganglionic infections.

4. Efficacy of a nucleic acid free herpetic subunit vaccine.

5. Herpes simplex virus type 1-induced hydrocephalus in mice.

6. Experimental ulcerative herpetic keratitis. I. Systemic immune responses and resistance to corneal infection.

7. Crossed immunoelectrophoretic studies of the solubility immunogenicity of herpes simplex virus antigens.

8. Failure of a subunit bovine herpesvirus 1 vaccine to protect against experimental respiratory disease in calves.

9. Animal studies on the efficacy of vaccination against recurrent herpes.

10. Immune response to a DNA free herpes simplex vaccine in man.