Literature DB >> 18712084

[Use of laws of interelement interactions for understanding of mechanisms of various human diseases].

G K Barashkov, L I Zaĭtseva.   

Abstract

The review considers the basic laws of interaction of elements in real physiological conditions of metabolism. The law of replacement and two it consequences have been formulated taking into account a major principle of cybernetics, the feedback principle. A rule of a fractional threshold and the law of toxicity based on the Mertz's rules have been formulated. These laws have been used here for consideration of mechanisms of occurrence and development of apoptosis and also side-effects of statins. Study of bioinorganic mechanisms of different diseases is a erspective way for search of complex connections of metals and ligands, capable to interaction with initiators of chain reactions, and for a finding of substances--inhibitors these reactions.

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Year:  2008        PMID: 18712084

Source DB:  PubMed          Journal:  Biomed Khim        ISSN: 2310-6905


  1 in total

1.  Synthesis of Bis(Isoxazol-4-Ylmethylsulfanyl)Alkanes and Some Metal Complexes as a Hepatoprotective Agents.

Authors:  Vnira Rakhimovna Akhmetova; Rozalia Akramovna Galimova; Nail Salavatovich Akhmadiev; Albina Midkhatovna Galimova; Ravil Akhmetzyanovich Khisamutdinov; Galiya Maratovna Nurtdinova; Eduard Feliksovich Agletdinov; Valery Alekseevich Kataev
Journal:  Adv Pharm Bull       Date:  2018-06-19
  1 in total

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