OBJECTIVE: To compare outcomes following abdominal surgery with or without the use of chewing gum in the early postoperative period. DATA SOURCES: MEDLINE, Embase, Ovid, and Cochrane databases. STUDY SELECTION: Randomized controlled trials reporting 1 or more outcomes related to functional postoperative recovery. Study quality was assessed using a validated scale. DATA EXTRACTION: Time to the first passage of flatus, time to first bowel movement, and length of postoperative stay. DATA SYNTHESIS: Five trials (158 patients) satisfied the inclusion criteria. Time (in days) for the patient to pass flatus (weighted mean difference [WMD], - 0.66; 95% confidence interval [CI], - 1.11 to - 0.20; P = .005) and the time until the first bowel movement (WMD, - 1.10; 95% CI, - 1.79 to - 0.42; P = .002) were significantly reduced in the chewing gum group compared with controls. However, both of these results demonstrated significant heterogeneity. Postoperative length of stay was also reduced in the chewing gum group by longer than 1 day (WMD, - 1.25; 95% CI, - 3.27 to 0.77; P = .23); however, this result was not statistically significant. This result was significant when studies that explicitly included patients with stomas being formed during the surgery were excluded (WMD, - 2.46; 95% CI, - 3.14 to - 1.79; P < .001), with no significant heterogeneity. CONCLUSIONS: Chewing gum may enhance intestinal recovery following colectomy and reduce the length of hospital stay. Owing to the potential for substantial cost savings, larger-scale, blinded, randomized controlled trials with placebo arms are warranted.
OBJECTIVE: To compare outcomes following abdominal surgery with or without the use of chewing gum in the early postoperative period. DATA SOURCES: MEDLINE, Embase, Ovid, and Cochrane databases. STUDY SELECTION: Randomized controlled trials reporting 1 or more outcomes related to functional postoperative recovery. Study quality was assessed using a validated scale. DATA EXTRACTION: Time to the first passage of flatus, time to first bowel movement, and length of postoperative stay. DATA SYNTHESIS: Five trials (158 patients) satisfied the inclusion criteria. Time (in days) for the patient to pass flatus (weighted mean difference [WMD], - 0.66; 95% confidence interval [CI], - 1.11 to - 0.20; P = .005) and the time until the first bowel movement (WMD, - 1.10; 95% CI, - 1.79 to - 0.42; P = .002) were significantly reduced in the chewing gum group compared with controls. However, both of these results demonstrated significant heterogeneity. Postoperative length of stay was also reduced in the chewing gum group by longer than 1 day (WMD, - 1.25; 95% CI, - 3.27 to 0.77; P = .23); however, this result was not statistically significant. This result was significant when studies that explicitly included patients with stomas being formed during the surgery were excluded (WMD, - 2.46; 95% CI, - 3.14 to - 1.79; P < .001), with no significant heterogeneity. CONCLUSIONS: Chewing gum may enhance intestinal recovery following colectomy and reduce the length of hospital stay. Owing to the potential for substantial cost savings, larger-scale, blinded, randomized controlled trials with placebo arms are warranted.
Authors: Hasan Al Chalabi; Dara O Kavanagh; Lana Hassan; Kate O Donnell; Emmeline Nugent; Emmet Andrews; Frank B V Keane; Diarmuid S O'Riordain; Andrew Miller; Paul Neary Journal: Int J Colorectal Dis Date: 2010-02-23 Impact factor: 2.571
Authors: Joseph C Carmichael; Deborah S Keller; Gabriele Baldini; Liliana Bordeianou; Eric Weiss; Lawrence Lee; Marylise Boutros; James McClane; Scott R Steele; Liane S Feldman Journal: Surg Endosc Date: 2017-08-03 Impact factor: 4.584
Authors: Gary Deng; W Douglas Wong; Jose Guillem; Yi Chan; Theresa Affuso; K Simon Yeung; Marci Coleton; Daniel Sjoberg; Andrew Vickers; Barrie Cassileth Journal: Ann Surg Oncol Date: 2012-11-28 Impact factor: 5.344