Literature DB >> 18710712

Recombinant human leukemia inhibitory factor does not improve implantation and pregnancy outcomes after assisted reproductive techniques in women with recurrent unexplained implantation failure.

Peter R Brinsden1, Veronica Alam, Beatrice de Moustier, Patrick Engrand.   

Abstract

In this randomized, double-blind, placebo-controlled, multicenter study, women (n = 149) with a history of at least two unexplained implantation failures after assisted reproductive techniques received recombinant human leukemia inhibitory factor, 150 microg SC twice daily for 7 days, or placebo. The clinical pregnancy rate after ET was significantly lower in patients receiving recombinant human leukemia inhibitory factor than in those receiving placebo (17.6% vs. 34.0%, respectively).

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Year:  2008        PMID： 18710712     DOI： 10.1016/j.fertnstert.2008.06.047

Source DB:  PubMed          Journal:  Fertil Steril        ISSN： 0015-0282            Impact factor:   7.329


  21 in total

1.  Research resource: interactome of human embryo implantation: identification of gene expression pathways, regulation, and integrated regulatory networks.

Authors:  Signe Altmäe; Jüri Reimand; Outi Hovatta; Pu Zhang; Juha Kere; Triin Laisk; Merli Saare; Maire Peters; Jaak Vilo; Anneli Stavreus-Evers; Andres Salumets
Journal:  Mol Endocrinol       Date:  2011-11-10

Review 2.  Implantation failure: molecular mechanisms and clinical treatment.

Authors:  Hakan Cakmak; Hugh S Taylor
Journal:  Hum Reprod Update       Date:  2010-08-21       Impact factor: 15.610

Review 3.  Guidelines for the design, analysis and interpretation of 'omics' data: focus on human endometrium.

Authors:  Signe Altmäe; Francisco J Esteban; Anneli Stavreus-Evers; Carlos Simón; Linda Giudice; Bruce A Lessey; Jose A Horcajadas; Nick S Macklon; Thomas D'Hooghe; Cristina Campoy; Bart C Fauser; Lois A Salamonsen; Andres Salumets
Journal:  Hum Reprod Update       Date:  2013-09-29       Impact factor: 15.610

Review 4.  Leukemia inhibitory factor (LIF).

Authors:  Nicos A Nicola; Jeffrey J Babon
Journal:  Cytokine Growth Factor Rev       Date:  2015-07-04       Impact factor: 7.638

Review 5.  What is the contribution of embryo-endometrial asynchrony to implantation failure?

Authors:  Wan-Tinn Teh; John McBain; Peter Rogers
Journal:  J Assist Reprod Genet       Date:  2016-08-01       Impact factor: 3.412

Review 6.  Assessment and treatment of repeated implantation failure (RIF).

Authors:  Alex Simon; Neri Laufer
Journal:  J Assist Reprod Genet       Date:  2012-09-14       Impact factor: 3.412

7.  Insufficient Angiogenesis: Cause of Abnormally Thin Endometrium in Subfertile Patients?

Authors:  Joachim Alfer; Lars Happel; Ralf Dittrich; Matthias W Beckmann; Arndt Hartmann; Andreas Gaumann; Volker U Buck; Irmgard Classen-Linke
Journal:  Geburtshilfe Frauenheilkd       Date:  2017-07-17       Impact factor: 2.915

Review 8.  Mechanisms of implantation: strategies for successful pregnancy.

Authors:  Jeeyeon Cha; Xiaofei Sun; Sudhansu K Dey
Journal:  Nat Med       Date:  2012-12       Impact factor: 53.440

Review 9.  Biomarkers in reproductive medicine: the promise, and can it be fulfilled?

Authors:  Stephen S Palmer; Kurt T Barnhart
Journal:  Fertil Steril       Date:  2012-12-14       Impact factor: 7.329

Review 10.  Minireview: Steroid-regulated paracrine mechanisms controlling implantation.

Authors:  Sandeep Pawar; Alison M Hantak; Indrani C Bagchi; Milan K Bagchi
Journal:  Mol Endocrinol       Date:  2014-07-22
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