Literature DB >> 18710211

Knowledge based prediction of ligand binding modes and rational inhibitor design for kinase drug discovery.

Arup K Ghose1, Torsten Herbertz, Douglas A Pippin, Joseph M Salvino, John P Mallamo.   

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Year:  2008        PMID： 18710211     DOI： 10.1021/jm800475y

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  34 in total

1.  Computational Modeling of Kinase Inhibitor Selectivity.

Authors:  Govindan Subramanian; Manish Sud
Journal:  ACS Med Chem Lett       Date:  2010-07-28       Impact factor: 4.345

2.  Measuring and interpreting the selectivity of protein kinase inhibitors.

Authors:  Lynette A Smyth; Ian Collins
Journal:  J Chem Biol       Date:  2009-06-06

Review 3.  The impact of GPCR structures on pharmacology and structure-based drug design.

Authors:  Miles Congreve; Fiona Marshall
Journal:  Br J Pharmacol       Date:  2009-11-13       Impact factor: 8.739

4.  Can structural features of kinase receptors provide clues on selectivity and inhibition? A molecular modeling study.

Authors:  Sarangan Ravichandran; Brian T Luke; Jack R Collins
Journal:  J Mol Graph Model       Date:  2015-01-12       Impact factor: 2.518

Review 5.  The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment.

Authors:  Randy Johnson; Georg Halder
Journal:  Nat Rev Drug Discov       Date:  2013-12-13       Impact factor: 84.694

6.  Protein kinase-inhibitor database: structural variability of and inhibitor interactions with the protein kinase P-loop.

Authors:  Ronak Y Patel; Robert J Doerksen
Journal:  J Proteome Res       Date:  2010-09-03       Impact factor: 4.466

7.  Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core.

Authors:  Tao Yu; Jayaram R Tagat; Angela D Kerekes; Ronald J Doll; Yonglian Zhang; Yushi Xiao; Sara Esposite; David B Belanger; Patrick J Curran; Amit K Mandal; M Arshad Siddiqui; Neng-Yang Shih; Andrea D Basso; Ming Liu; Kimberly Gray; Seema Tevar; Jennifer Jones; Suining Lee; Lianzhu Liang; Samad Ponery; Elizabeth B Smith; Alan Hruza; Johannes Voigt; Lata Ramanathan; Winifred Prosise; Mengwei Hu
Journal:  ACS Med Chem Lett       Date:  2010-06-07       Impact factor: 4.345

8.  Blocking UV-induced eIF2alpha phosphorylation with small molecule inhibitors of GCN2.

Authors:  Francis Robert; Chris Williams; Yifei Yan; Elizabeth Donohue; Regina Cencic; Stephen K Burley; Jerry Pelletier
Journal:  Chem Biol Drug Des       Date:  2009-07       Impact factor: 2.817

9.  From imide to lactam metallo-pyridocarbazoles: distinct scaffolds for the design of selective protein kinase inhibitors.

Authors:  Nicholas Pagano; Eric Y Wong; Tom Breiding; Haidong Liu; Alexander Wilbuer; Howard Bregman; Qi Shen; Scott L Diamond; Eric Meggers
Journal:  J Org Chem       Date:  2009-12-04       Impact factor: 4.354

10.  p3d--Python module for structural bioinformatics.

Authors:  Christian Fufezan; Michael Specht
Journal:  BMC Bioinformatics       Date:  2009-08-21       Impact factor: 3.169
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