Literature DB >> 18703351

Implementation of DART and DESI ionization on a fieldable mass spectrometer.

J Mitchell Wells1, Michael J Roth, Adam D Keil, John W Grossenbacher, Dina R Justes, Garth E Patterson, Dennis J Barket.   

Abstract

A recently developed prototype mobile laboratory mass spectrometer, incorporating an atmospheric pressure ionization (API) interface, is described. This system takes advantage of the small size, lower voltage requirements, and tandem MS abilities of the cylindrical ion trap mass analyzer. The prototype API MS uses small, low-power pumps to fit into a 0.1-m(3) self-contained package weighing <45 kg. This instrument has been adapted to allow rapid interfacing to electrospray ionization, desorption electrospray ionization, and direct analysis in real-time sources. Initial data indicate that these techniques provide rapid detection and identification of compounds for quality control, homeland security, and forensic applications. In addition, this instrument is self-contained and compact, making it ideally extensible to mobile laboratory and field analyses. Initial MS and MS/MS data for analyses of drugs, food, and explosives are presented herein.

Entities:  

Year:  2008        PMID: 18703351     DOI: 10.1016/j.jasms.2008.06.028

Source DB:  PubMed          Journal:  J Am Soc Mass Spectrom        ISSN: 1044-0305            Impact factor:   3.109


  31 in total

1.  Miniature cylindrical ion trap mass spectrometer.

Authors:  Garth E Patterson; Andrew J Guymon; Leah S Riter; Mike Everly; Jens Griep-Raming; Brian C Laughlin; Zheng Ouyang; R Graham Cooks
Journal:  Anal Chem       Date:  2002-12-15       Impact factor: 6.986

2.  Desorption electrospray ionization of explosives on surfaces: sensitivity and selectivity enhancement by reactive desorption electrospray ionization.

Authors:  Ismael Cotte-Rodríguez; Zoltán Takáts; Nari Talaty; Huanwen Chen; R Graham Cooks
Journal:  Anal Chem       Date:  2005-11-01       Impact factor: 6.986

3.  Versatile new ion source for the analysis of materials in open air under ambient conditions.

Authors:  Robert B Cody; James A Laramée; H Dupont Durst
Journal:  Anal Chem       Date:  2005-04-15       Impact factor: 6.986

4.  Direct high-resolution peptide and protein analysis by desorption electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry.

Authors:  Michael S Bereman; Leonard Nyadong; Facundo M Fernandez; David C Muddiman
Journal:  Rapid Commun Mass Spectrom       Date:  2006       Impact factor: 2.419

5.  Liquid chromatography electrospray tandem mass spectrometric and desorption electrospray ionization tandem mass spectrometric analysis of chemical warfare agents in office media typically collected during a forensic investigation.

Authors:  P A D'Agostino; J R Hancock; C L Chenier; C R Jackson Lepage
Journal:  J Chromatogr A       Date:  2006-02-09       Impact factor: 4.759

6.  Desorption electrospray ionization of aerosol particles.

Authors:  Jianan Dong; Yohannes H Rezenom; Kermit K Murray
Journal:  Rapid Commun Mass Spectrom       Date:  2007       Impact factor: 2.419

7.  A miniature cylindrical quadrupole ion trap:  simulation and experiment.

Authors:  E R Badman; R C Johnson; W R Plass; R G Cooks
Journal:  Anal Chem       Date:  1998-12-01       Impact factor: 6.986

8.  Ambient generation of fatty acid methyl ester ions from bacterial whole cells by direct analysis in real time (DART) mass spectrometry.

Authors:  Carrie Y Pierce; John R Barr; Robert B Cody; Robert F Massung; Adrian R Woolfitt; Hercules Moura; Herbert A Thompson; Facundo M Fernandez
Journal:  Chem Commun (Camb)       Date:  2006-11-24       Impact factor: 6.222

Review 9.  Modern developments in gas chromatography-mass spectrometry-based environmental analysis.

Authors:  F J Santos; M T Galceran
Journal:  J Chromatogr A       Date:  2003-06-06       Impact factor: 4.759

10.  Rapid trace detection of triacetone triperoxide (TATP) by complexation reactions during desorption electrospray ionization.

Authors:  Ismael Cotte-Rodríguez; Hao Chen; R Graham Cooks
Journal:  Chem Commun (Camb)       Date:  2006-01-12       Impact factor: 6.222

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  8 in total

1.  Direct detection of pharmaceuticals and personal care products from aqueous samples with thermally-assisted desorption electrospray ionization mass spectrometry.

Authors:  Ian S Campbell; Alain T Ton; Christopher C Mulligan
Journal:  J Am Soc Mass Spectrom       Date:  2011-05-05       Impact factor: 3.109

Review 2.  What can we learn from ambient ionization techniques?

Authors:  Huanwen Chen; Gerardo Gamez; Renato Zenobi
Journal:  J Am Soc Mass Spectrom       Date:  2009-08-13       Impact factor: 3.109

Review 3.  The interface between forensic science and technology: how technology could cause a paradigm shift in the role of forensic institutes in the criminal justice system.

Authors:  Ate Kloosterman; Anna Mapes; Zeno Geradts; Erwin van Eijk; Carola Koper; Jorrit van den Berg; Saskia Verheij; Marcel van der Steen; Arian van Asten
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-08-05       Impact factor: 6.237

4.  Analytical Validation of a Portable Mass Spectrometer Featuring Interchangeable, Ambient Ionization Sources for High Throughput Forensic Evidence Screening.

Authors:  Zachary E Lawton; Angelica Traub; William L Fatigante; Jose Mancias; Adam E O'Leary; Seth E Hall; Jamie R Wieland; Herbert Oberacher; Michael C Gizzi; Christopher C Mulligan
Journal:  J Am Soc Mass Spectrom       Date:  2016-12-20       Impact factor: 3.109

5.  A Theoretical Method for Characterizing Nonlinear Effects in Paul Traps with Added Octopole Field.

Authors:  Caiqiao Xiong; Xiaoyu Zhou; Ning Zhang; Lingpeng Zhan; Yongtai Chen; Suming Chen; Zongxiu Nie
Journal:  J Am Soc Mass Spectrom       Date:  2015-04-30       Impact factor: 3.109

6.  Enhancing Performance of Liquid Sample Desorption Electrospray Ionization Mass Spectrometry Using Trap and Capillary Columns.

Authors:  Si Cheng; Jun Wang; Yi Cai; Joseph A Loo; Hao Chen
Journal:  Int J Mass Spectrom       Date:  2015-12-03       Impact factor: 1.986

Review 7.  Recent advances in ambient mass spectrometry of trace explosives.

Authors:  Thomas P Forbes; Edward Sisco
Journal:  Analyst       Date:  2018-04-30       Impact factor: 4.616

8.  Proof of Concept Coded Aperture Miniature Mass Spectrometer Using a Cycloidal Sector Mass Analyzer, a Carbon Nanotube (CNT) Field Emission Electron Ionization Source, and an Array Detector.

Authors:  Jason J Amsden; Philip J Herr; David M W Landry; William Kim; Raul Vyas; Charles B Parker; Matthew P Kirley; Adam D Keil; Kristin H Gilchrist; Erich J Radauscher; Stephen D Hall; James B Carlson; Nicholas Baldasaro; David Stokes; Shane T Di Dona; Zachary E Russell; Sonia Grego; Steven J Edwards; Roger P Sperline; M Bonner Denton; Brian R Stoner; Michael E Gehm; Jeffrey T Glass
Journal:  J Am Soc Mass Spectrom       Date:  2017-10-19       Impact factor: 3.109

  8 in total

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