Literature DB >> 18703320

Medial temporal N-acetyl-aspartate in pediatric major depression.

Frank P MacMaster1, Gregory J Moore, Aileen Russell, Yousha Mirza, S Preeya Taormina, Christian Buhagiar, David R Rosenberg.   

Abstract

The medial temporal cortex (MTC) has been implicated in the pathogenesis of pediatric major depressive disorder (MDD). Eleven MDD case-control pairs underwent proton magnetic resonance spectroscopic imaging. N-acetyl-aspartate was lower in the left MTC (27%) in MDD patients versus controls. Lower N-acetyl-aspartate concentrations in MDD patients may reflect reduced neuronal viability.

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Year:  2008        PMID： 18703320      PMCID： PMC2653710          DOI： 10.1016/j.pscychresns.2007.12.022

Source DB:  PubMed          Journal:  Psychiatry Res        ISSN： 0165-1781            Impact factor:   3.222


  15 in total

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Journal:  J Am Acad Child Adolesc Psychiatry       Date:  1991-05       Impact factor: 8.829

2.  Quantitation of automated single-voxel proton MRS using cerebral water as an internal reference.

Authors:  B J Soher; R E Hurd; N Sailasuta; P B Barker
Journal:  Magn Reson Med       Date:  1996-09       Impact factor: 4.668

3.  Fast proton spectroscopic imaging of human brain using multiple spin-echoes.

Authors:  J H Duyn; C T Moonen
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4.  The possibility of neurotoxicity in the hippocampus in major depression: a primer on neuron death.

Authors:  R M Sapolsky
Journal:  Biol Psychiatry       Date:  2000-10-15       Impact factor: 13.382

5.  Hippocampal neurochemical pathology in patients at first episode of affective psychosis: a proton magnetic resonance spectroscopic imaging study.

Authors:  Giuseppe Blasi; Alessandro Bertolino; Flora Brudaglio; Domenico Sciota; Mario Altamura; Nicola Antonucci; Tommaso Scarabino; Daniel R Weinberger; Marcello Nardini
Journal:  Psychiatry Res       Date:  2004-07-30       Impact factor: 3.222

6.  Increased medial thalamic choline found in pediatric patients with obsessive-compulsive disorder versus major depression or healthy control subjects: a magnetic resonance spectroscopy study.

Authors:  Ethan A Smith; Aileen Russell; Elisa Lorch; S Preeya Banerjee; Michelle Rose; Jennifer Ivey; Rashmi Bhandari; Gregory J Moore; David R Rosenberg
Journal:  Biol Psychiatry       Date:  2003-12-15       Impact factor: 13.382

7.  Course of illness, hippocampal function, and hippocampal volume in major depression.

Authors:  Glenda M MacQueen; Stephanie Campbell; Bruce S McEwen; Kathryn Macdonald; Shigeko Amano; Russell T Joffe; Claude Nahmias; L Trevor Young
Journal:  Proc Natl Acad Sci U S A       Date:  2003-01-24       Impact factor: 11.205

8.  24-hour cortisol measures in adolescents with major depression: a controlled study.

Authors:  R E Dahl; N D Ryan; J Puig-Antich; N A Nguyen; M al-Shabbout; V A Meyer; J Perel
Journal:  Biol Psychiatry       Date:  1991-07-01       Impact factor: 13.382

9.  Proton magnetic resonance spectroscopic imaging in pediatric major depression.

Authors:  Tiffany R Farchione; Gregory J Moore; David R Rosenberg
Journal:  Biol Psychiatry       Date:  2002-07-15       Impact factor: 13.382

10.  Amygdala and hippocampal volumes in familial early onset major depressive disorder.

Authors:  Frank P MacMaster; Yousha Mirza; Philip R Szeszko; Lauren E Kmiecik; Phillip C Easter; S Preeya Taormina; Michelle Lynch; Michelle Rose; Gregory J Moore; David R Rosenberg
Journal:  Biol Psychiatry       Date:  2007-07-20       Impact factor: 13.382
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  7 in total

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Authors:  Erin Fallucca; Frank P MacMaster; Joseph Haddad; Phillip Easter; Rachel Dick; Geoffrey May; Jeffrey A Stanley; Carrie Rix; David R Rosenberg
Journal:  Arch Gen Psychiatry       Date:  2011-05

Review 2.  Toward dysfunctional connectivity: a review of neuroimaging findings in pediatric major depressive disorder.

Authors:  Leslie A Hulvershorn; Kathryn Cullen; Amit Anand
Journal:  Brain Imaging Behav       Date:  2011-12       Impact factor: 3.978

3.  Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden.

Authors:  Javier de Diego-Adeliño; Maria J Portella; Beatriz Gómez-Ansón; Olga López-Moruelo; Maria Serra-Blasco; Yolanda Vives; Dolors Puigdemont; Rosario Pérez-Egea; Enric Álvarez; Víctor Pérez
Journal:  J Psychiatry Neurosci       Date:  2013-03       Impact factor: 6.186

4.  Proton magnetic resonance spectroscopy (MRS) in on-line game addiction.

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Journal:  J Psychiatr Res       Date:  2014-07-16       Impact factor: 4.791

5.  Increased ventricular cerebrospinal fluid lactate in depressed adolescents.

Authors:  K A L Bradley; X Mao; J A C Case; G Kang; D C Shungu; V Gabbay
Journal:  Eur Psychiatry       Date:  2016-01-21       Impact factor: 5.361

6.  Review: magnetic resonance spectroscopy studies of pediatric major depressive disorder.

Authors:  Douglas G Kondo; Tracy L Hellem; Young-Hoon Sung; Namkug Kim; Eun-Kee Jeong; Kristen K Delmastro; Xianfeng Shi; Perry F Renshaw
Journal:  Depress Res Treat       Date:  2010-10-04

7.  Cortical thickness in youth with major depressive disorder.

Authors:  Stephanie Reynolds; Normand Carrey; Natalia Jaworska; Lisa Marie Langevin; Xiao-Ru Yang; Frank P Macmaster
Journal:  BMC Psychiatry       Date:  2014-03-20       Impact factor: 3.630
  7 in total

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