| Literature DB >> 18700791 |
Benjamin A Garcia1, C Eric Thomas, Neil L Kelleher, Craig A Mizzen.
Abstract
Analyses of histone H3 from 10 rat tissues using a Middle Down proteomics platform revealed tissue-specific differences in their expression and global PTM abundance. ESI/FTMS with electron capture dissociation showed that, in general, these proteins were hypomodified in heart, liver and testes. H3.3 was hypermodified compared to H3.2 in some, but not all tissues. In addition, a novel rat testes-specific H3 protein was identified with this approach.Entities:
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Year: 2008 PMID: 18700791 PMCID: PMC2615678 DOI: 10.1021/pr800044q
Source DB: PubMed Journal: J Proteome Res ISSN: 1535-3893 Impact factor: 4.466