| Literature DB >> 18698779 |
Johanna Andersson1, Shiming Li, Per Lincoln, Joakim Andréasson.
Abstract
The dramatically different DNA-binding properties of the two isomeric forms of a photochromic spiropyran have been demonstrated, enabling photoswitched DNA binding. The closed, UV-absorbing form shows no signs of interaction with DNA. Upon UV exposure the spiropyran is isomerized to the open form that binds to DNA by intercalation. The process is fully reversible as the corresponding dissociation process is induced by visible light.Mesh:
Substances:
Year: 2008 PMID: 18698779 DOI: 10.1021/ja801968f
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419