Literature DB >> 18693764

Design and synthesis of medium-ring lactam libraries inspired by octalactin a. A convergent-divergent approach.

Neil Brown1, Ge Gao, Machiko Minatoya, Baohan Xie, David Vandervelde, Gerald H Lushington, Jean-Pierre H Perchellet, Elisabeth M Perchellet, Kyle R Crow, Keith R Buszek.   

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Year:  2008        PMID： 18693764      PMCID： PMC2872934          DOI： 10.1021/cc8001102

Source DB:  PubMed          Journal:  J Comb Chem        ISSN： 1520-4766


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  7 in total

1.  A systematic SAR study of C10 modified paclitaxel analogues using a combinatorial approach.

Authors:  Yanbin Liu; Syed M Ali; Thomas C Boge; Gunda I Georg; Samuel Victory; Jan Zygmunt; Rebecca T Marquez; Richard H Himes
Journal:  Comb Chem High Throughput Screen       Date:  2002-02       Impact factor: 1.339

2.  Total synthesis of natural 8- and 9-membered lactones: recent advancements in medium-sized ring formation.

Authors:  Isamu Shiina
Journal:  Chem Rev       Date:  2007-01       Impact factor: 60.622

3.  Novel Algorithms for the Identification of Biologically Informative Chemical Diversity Metrics.

Authors:  Bhargav Theertham; Jenna L Wang; Jianwen Fang; Gerald H Lushington
Journal:  Curr Comput Aided Drug Des       Date:  2008-03-01       Impact factor: 1.606

4.  Synthesis and evaluation of paclitaxel C7 derivatives: solution phase synthesis of combinatorial libraries.

Authors:  L Bhat; Y Liu; S F Victory; R H Himes; G I Georg
Journal:  Bioorg Med Chem Lett       Date:  1998-11-17       Impact factor: 2.823

5.  Antitumor activity of novel octalactin A analogs in murine leukemia cells in vitro.

Authors:  J P Perchellet; E M Perchellet; S W Newell; J A Freeman; J B Ladesich; Y Jeong; N Sato; K Buszek
Journal:  Anticancer Res       Date:  1998 Jan-Feb       Impact factor: 2.480

6.  The synthesis of P-chiral amino acid-derived phosphonamidic anhydrides.

Authors:  K T Sprott; P R Hanson
Journal:  J Org Chem       Date:  2000-07-28       Impact factor: 4.354

7.  Improved method for the diimide reduction of multiple bonds on solid-supported substrates.

Authors:  Keith R Buszek; Neil Brown
Journal:  J Org Chem       Date:  2007-03-17       Impact factor: 4.354
  7 in total
  5 in total

1.  A Practical, Multi-gram Synthesis of (±)-Herbindole A, (±)-Herbindole B, and (±)-Herbindole C from a Common Intermediate via 6,7-Indole Aryne Cycloaddition and Pd(0)-Catalyzed Cross-Coupling Reactions.

Authors:  Nalin Chandrasoma; Sivadarshini Pathmanathan; Keith R Buszek
Journal:  Tetrahedron Lett       Date:  2015-06-03       Impact factor: 2.415

2.  Application of 6,7-indole aryne cycloaddition and Pd(0)-catalyzed Suzuki-Miyaura and Buchwald-Hartwig cross-coupling reactions for the preparation of annulated indole libraries.

Authors:  Paul D Thornton; Neil Brown; David Hill; Ben Neuenswander; Gerald H Lushington; Conrad Santini; Keith R Buszek
Journal:  ACS Comb Sci       Date:  2011-06-30       Impact factor: 3.784

3.  Novel synthetic inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase activity that inhibit tumor cell proliferation and are structurally unrelated to existing statins.

Authors:  Jean-Pierre H Perchellet; Elisabeth M Perchellet; Kyle R Crow; Keith R Buszek; Neil Brown; Sampathkumar Ellappan; Ge Gao; Diheng Luo; Machiko Minatoya; Gerald H Lushington
Journal:  Int J Mol Med       Date:  2009-11       Impact factor: 4.101

4.  Synthesis of Benzannulated Medium-ring Lactams via a Tandem Oxidative Dearomatization-Ring Expansion Reaction.

Authors:  Tezcan Guney; Todd A Wenderski; Matthew W Boudreau; Derek S Tan
Journal:  Chemistry       Date:  2018-08-02       Impact factor: 5.236

5.  Biomimetic diversity-oriented synthesis of benzannulated medium rings via ring expansion.

Authors:  Renato A Bauer; Todd A Wenderski; Derek S Tan
Journal:  Nat Chem Biol       Date:  2012-11-18       Impact factor: 15.040
  5 in total

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