Literature DB >> 18691544

Even cancers want commitment: lineage identity and medulloblastoma formation.

Charles G Eberhart1.   

Abstract

In this issue of Cancer Cell, Yang et al. (2008) and Schüller et al. (2008) show that Hedgehog activation in either multipotent neural stem cells or developmentally restricted progenitors causes only medulloblastomas to form. These data suggest that some stem cell-derived tumors must commit to a specific lineage in order to grow.

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Year:  2008        PMID： 18691544      PMCID： PMC4512647          DOI： 10.1016/j.ccr.2008.07.011

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  11 in total

Review 1.  Morphology, molecular codes, and circuitry produce the three-dimensional complexity of the cerebellum.

Authors:  Roy V Sillitoe; Alexandra L Joyner
Journal:  Annu Rev Cell Dev Biol       Date:  2007       Impact factor: 13.827

2.  Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.

Authors:  T Pietsch; A Waha; A Koch; J Kraus; S Albrecht; J Tonn; N Sörensen; F Berthold; B Henk; N Schmandt; H K Wolf; A von Deimling; B Wainwright; G Chenevix-Trench; O D Wiestler; C Wicking
Journal:  Cancer Res       Date:  1997-06-01       Impact factor: 12.701

3.  HEDGEHOG-GLI1 signaling regulates human glioma growth, cancer stem cell self-renewal, and tumorigenicity.

Authors:  Virginie Clement; Pilar Sanchez; Nicolas de Tribolet; Ivan Radovanovic; Ariel Ruiz i Altaba
Journal:  Curr Biol       Date:  2006-12-28       Impact factor: 10.834

4.  Loss of patched and disruption of granule cell development in a pre-neoplastic stage of medulloblastoma.

Authors:  Trudy G Oliver; Tracy Ann Read; Jessica D Kessler; Anriada Mehmeti; Jonathan F Wells; Trang T T Huynh; Simon M Lin; Robert J Wechsler-Reya
Journal:  Development       Date:  2005-04-20       Impact factor: 6.868

Review 5.  Lineage dependency and lineage-survival oncogenes in human cancer.

Authors:  Levi A Garraway; William R Sellers
Journal:  Nat Rev Cancer       Date:  2006-08       Impact factor: 60.716

6.  Conserved mechanisms across development and tumorigenesis revealed by a mouse development perspective of human cancers.

Authors:  Alvin T Kho; Qing Zhao; Zhaohui Cai; Atul J Butte; John Y H Kim; Scott L Pomeroy; David H Rowitch; Isaac S Kohane
Journal:  Genes Dev       Date:  2004-03-15       Impact factor: 11.361

7.  Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells.

Authors:  Zeng-Jie Yang; Tammy Ellis; Shirley L Markant; Tracy-Ann Read; Jessica D Kessler; Melissa Bourboulas; Ulrich Schüller; Robert Machold; Gord Fishell; David H Rowitch; Brandon J Wainwright; Robert J Wechsler-Reya
Journal:  Cancer Cell       Date:  2008-08-12       Impact factor: 31.743

8.  Cyclopamine-mediated hedgehog pathway inhibition depletes stem-like cancer cells in glioblastoma.

Authors:  Eli E Bar; Aneeka Chaudhry; Alex Lin; Xing Fan; Karisa Schreck; William Matsui; Sara Piccirillo; Angelo L Vescovi; Francesco DiMeco; Alessandro Olivi; Charles G Eberhart
Journal:  Stem Cells       Date:  2007-07-12       Impact factor: 6.277

9.  Acquisition of granule neuron precursor identity is a critical determinant of progenitor cell competence to form Shh-induced medulloblastoma.

Authors:  Ulrich Schüller; Vivi M Heine; Junhao Mao; Alvin T Kho; Allison K Dillon; Young-Goo Han; Emmanuelle Huillard; Tao Sun; Azra H Ligon; Ying Qian; Qiufu Ma; Arturo Alvarez-Buylla; Andrew P McMahon; David H Rowitch; Keith L Ligon
Journal:  Cancer Cell       Date:  2008-08-12       Impact factor: 31.743

Review 10.  The 2007 WHO classification of tumours of the central nervous system.

Authors:  David N Louis; Hiroko Ohgaki; Otmar D Wiestler; Webster K Cavenee; Peter C Burger; Anne Jouvet; Bernd W Scheithauer; Paul Kleihues
Journal:  Acta Neuropathol       Date:  2007-07-06       Impact factor: 17.088
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  12 in total

1.  Reactive Oxygen Species Signaling Promotes Hypoxia-Inducible Factor 1α Stabilization in Sonic Hedgehog-Driven Cerebellar Progenitor Cell Proliferation.

Authors:  Chad R Potts; M Hope Robinson; Nicholas W Eyrich; Victor Maximov; Anna M Kenney
Journal:  Mol Cell Biol       Date:  2019-04-02       Impact factor: 4.272

2.  β-Arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors.

Authors:  Susana R Parathath; Lori Anne Mainwaring; Africa Fernandez-L; Cemile G Guldal; Zaher Nahlé; Anna Marie Kenney
Journal:  Cell Cycle       Date:  2010-10-11       Impact factor: 4.534

3.  Atoh1 inhibits neuronal differentiation and collaborates with Gli1 to generate medulloblastoma-initiating cells.

Authors:  Olivier Ayrault; Haotian Zhao; Frederique Zindy; Chunxu Qu; Charles J Sherr; Martine F Roussel
Journal:  Cancer Res       Date:  2010-06-01       Impact factor: 12.701

Review 4.  Brain cancer propagating cells: biology, genetics and targeted therapies.

Authors:  Costas G Hadjipanayis; Erwin G Van Meir
Journal:  Trends Mol Med       Date:  2009-11-02       Impact factor: 11.951

5.  Sonic Hedgehog Signaling Drives Mitochondrial Fragmentation by Suppressing Mitofusins in Cerebellar Granule Neuron Precursors and Medulloblastoma.

Authors:  Anshu Malhotra; Abhinav Dey; Niyathi Prasad; Anna Marie Kenney
Journal:  Mol Cancer Res       Date:  2015-10-07       Impact factor: 5.852

Review 6.  Concise review: self-renewal in the central nervous system: neural stem cells from embryo to adult.

Authors:  Lidia De Filippis; Elena Binda
Journal:  Stem Cells Transl Med       Date:  2012-04-10       Impact factor: 6.940

7.  Hedgehog-mediated regulation of PPARγ controls metabolic patterns in neural precursors and shh-driven medulloblastoma.

Authors:  Bobby Bhatia; Chad R Potts; Cemile Guldal; SunPhil Choi; Andrey Korshunov; Stefan Pfister; Anna M Kenney; Zaher A Nahlé
Journal:  Acta Neuropathol       Date:  2012-03-11       Impact factor: 17.088

8.  Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation.

Authors:  A Fernandez-L; M Squatrito; P Northcott; A Awan; E C Holland; M D Taylor; Z Nahlé; A M Kenney
Journal:  Oncogene       Date:  2011-08-29       Impact factor: 9.867

9.  Mitogenic Sonic hedgehog signaling drives E2F1-dependent lipogenesis in progenitor cells and medulloblastoma.

Authors:  B Bhatia; M Hsieh; A M Kenney; Z Nahlé
Journal:  Oncogene       Date:  2010-10-04       Impact factor: 9.867

10.  A novel germline mutation in a patient with nevoid basal cell carcinoma syndrome showing cystic lesion in the lung.

Authors:  Ryo Miyata; Manabu Kurosawa; Masaaki Sato; Tomoya Kono; Yasutaka Takubo; Shinsaku Okai; Keisuke Yamada; Reiko Shinkura; Hiroshi Date; Fumihiko Matsuda
Journal:  Hum Genome Var       Date:  2015-06-11
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