| Literature DB >> 18690161 |
Abstract
The development of novel imaging agents and techniques is allowing some biological events to be imaged in vivo with magnetic resonance imaging (MRI) at the cellular and subcellular level. In this paper, the use of novel gadolinium chelates and superparamagnetic iron oxide nanoparticles for molecular MRI of the cardiovascular system is extensively reviewed. The physical properties of these imaging agents and the pulse sequences best suited to their visualization are extensively discussed. The application of molecular MRI in diseases of the vasculature and myocardium is then reviewed. The clinical experience to date, as well as the promise and potential impact of molecular MRI, is extensively discussed.Entities:
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Year: 2008 PMID: 18690161 PMCID: PMC2597277 DOI: 10.1097/RMR.0b013e318176c57b
Source DB: PubMed Journal: Top Magn Reson Imaging ISSN: 0899-3459