Literature DB >> 18689472

Role of phosphopantetheinyl transferase genes in antibiotic production by Streptomyces coelicolor.

Ya-Wen Lu1, Adrianna K San Roman, Amy M Gehring.   

Abstract

The phosphopantetheinyl transferase genes SCO5883 (redU) and SCO6673 were disrupted in Streptomyces coelicolor. The redU mutants did not synthesize undecylprodigiosin, while SCO6673 mutants failed to produce calcium-dependent antibiotic. Neither gene was essential for actinorhodin production or morphological development in S. coelicolor, although their mutation could influence these processes.

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Year:  2008        PMID： 18689472      PMCID： PMC2566214          DOI： 10.1128/JB.00865-08

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  31 in total

1.  Global analysis of growth phase responsive gene expression and regulation of antibiotic biosynthetic pathways in Streptomyces coelicolor using DNA microarrays.

Authors:  J Huang; C J Lih; K H Pan; S N Cohen
Journal:  Genes Dev       Date:  2001-12-01       Impact factor: 11.361

2.  RNA polymerase sigma factor that blocks morphological differentiation by Streptomyces coelicolor.

Authors:  A M Gehring; N J Yoo; R Losick
Journal:  J Bacteriol       Date:  2001-10       Impact factor: 3.490

3.  Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2).

Authors:  S D Bentley; K F Chater; A-M Cerdeño-Tárraga; G L Challis; N R Thomson; K D James; D E Harris; M A Quail; H Kieser; D Harper; A Bateman; S Brown; G Chandra; C W Chen; M Collins; A Cronin; A Fraser; A Goble; J Hidalgo; T Hornsby; S Howarth; C-H Huang; T Kieser; L Larke; L Murphy; K Oliver; S O'Neil; E Rabbinowitsch; M-A Rajandream; K Rutherford; S Rutter; K Seeger; D Saunders; S Sharp; R Squares; S Squares; K Taylor; T Warren; A Wietzorrek; J Woodward; B G Barrell; J Parkhill; D A Hopwood
Journal:  Nature       Date:  2002-05-09       Impact factor: 49.962

4.  Crystal structure of the surfactin synthetase-activating enzyme sfp: a prototype of the 4'-phosphopantetheinyl transferase superfamily.

Authors:  K Reuter; M R Mofid; M A Marahiel; R Ficner
Journal:  EMBO J       Date:  1999-12-01       Impact factor: 11.598

5.  Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites.

Authors:  S Omura; H Ikeda; J Ishikawa; A Hanamoto; C Takahashi; M Shinose; Y Takahashi; H Horikawa; H Nakazawa; T Osonoe; H Kikuchi; T Shiba; Y Sakaki; M Hattori
Journal:  Proc Natl Acad Sci U S A       Date:  2001-09-25       Impact factor: 11.205

6.  Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes.

Authors:  A M Cerdeño; M J Bibb; G L Challis
Journal:  Chem Biol       Date:  2001-08

7.  Cloning and analysis of the simocyclinone biosynthetic gene cluster of Streptomyces antibioticus Tü 6040.

Authors:  Ute Galm; Judith Schimana; Hans-Peter Fiedler; Jürgen Schmidt; Shu-Ming Li; Lutz Heide
Journal:  Arch Microbiol       Date:  2002-05-14       Impact factor: 2.552

8.  Activation of antibiotic biosynthesis by specified mutations in the rpoB gene (encoding the RNA polymerase beta subunit) of Streptomyces lividans.

Authors:  Haifeng Hu; Qin Zhang; Kozo Ochi
Journal:  J Bacteriol       Date:  2002-07       Impact factor: 3.490

9.  Complete genome sequence of the erythromycin-producing bacterium Saccharopolyspora erythraea NRRL23338.

Authors:  Markiyan Oliynyk; Markiyan Samborskyy; John B Lester; Tatiana Mironenko; Nataliya Scott; Shilo Dickens; Stephen F Haydock; Peter F Leadlay
Journal:  Nat Biotechnol       Date:  2007-03-18       Impact factor: 54.908

Review 10.  Principles of microbial alchemy: insights from the Streptomyces coelicolor genome sequence.

Authors:  Charles J Thompson; Doris Fink; Liem D Nguyen
Journal:  Genome Biol       Date:  2002-06-26       Impact factor: 13.583
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  13 in total

Review 1.  Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes.

Authors:  Richard H Baltz
Journal:  J Ind Microbiol Biotechnol       Date:  2015-09-12       Impact factor: 3.346

Review 2.  The phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for life.

Authors:  Joris Beld; Eva C Sonnenschein; Christopher R Vickery; Joseph P Noel; Michael D Burkart
Journal:  Nat Prod Rep       Date:  2014-01       Impact factor: 13.423

3.  Two bacterial group II phosphopantetheinyl transferases involved in both primary metabolism and secondary metabolism.

Authors:  Yue-Yue Wang; Xiao-Sheng Zhang; Ni-Ni Ren; Yuan-Yang Guo; Xin-Hang Jiang; Hui Jiang; Yu-Dong Li; Yong-Quan Li
Journal:  Curr Microbiol       Date:  2014-11-21       Impact factor: 2.188

4.  ClbP is a prototype of a peptidase subgroup involved in biosynthesis of nonribosomal peptides.

Authors:  Damien Dubois; Olivier Baron; Antony Cougnoux; Julien Delmas; Nathalie Pradel; Michèle Boury; Bernadette Bouchon; Marie-Agnès Bringer; Jean-Philippe Nougayrède; Eric Oswald; Richard Bonnet
Journal:  J Biol Chem       Date:  2011-07-27       Impact factor: 5.157

5.  Improvement of natamycin production by engineering of phosphopantetheinyl transferases in Streptomyces chattanoogensis L10.

Authors:  Hui Jiang; Yue-Yue Wang; Xin-Xin Ran; Wei-Ming Fan; Xin-Hang Jiang; Wen-Jun Guan; Yong-Quan Li
Journal:  Appl Environ Microbiol       Date:  2013-03-22       Impact factor: 4.792

6.  Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.

Authors:  John E Cronan; Jacob Thomas
Journal:  Methods Enzymol       Date:  2009       Impact factor: 1.600

Review 7.  Engineering microbial hosts for production of bacterial natural products.

Authors:  Mingzi M Zhang; Yajie Wang; Ee Lui Ang; Huimin Zhao
Journal:  Nat Prod Rep       Date:  2016-04-13       Impact factor: 13.423

8.  Genome plasticity and systems evolution in Streptomyces.

Authors:  Zhan Zhou; Jianying Gu; Yong-Quan Li; Yufeng Wang
Journal:  BMC Bioinformatics       Date:  2012-06-25       Impact factor: 3.169

9.  A hybrid NRPS-PKS gene cluster related to the bleomycin family of antitumor antibiotics in Alteromonas macleodii strains.

Authors:  Carolina Megumi Mizuno; Nikole E Kimes; Mario López-Pérez; Eva Ausó; Francisco Rodriguez-Valera; Rohit Ghai
Journal:  PLoS One       Date:  2013-09-19       Impact factor: 3.240

10.  A single Sfp-type phosphopantetheinyl transferase plays a major role in the biosynthesis of PKS and NRPS derived metabolites in Streptomyces ambofaciens ATCC23877.

Authors:  Robert Bunet; Ramona Riclea; Luisa Laureti; Laurence Hôtel; Cédric Paris; Jean-Michel Girardet; Dieter Spiteller; Jeroen S Dickschat; Pierre Leblond; Bertrand Aigle
Journal:  PLoS One       Date:  2014-01-31       Impact factor: 3.240
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