| Literature DB >> 18689428 |
Abstract
When investigating the change in a biomarker, it is often believed that at least two measurements are needed from each participant, and that those with only one measurement should be excluded. In this short note, we explain why this could lead to imprecise and biased estimates. Furthermore, we discuss a standard statistical method that handles such issues.Entities:
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Year: 2008 PMID: 18689428 PMCID: PMC2738849 DOI: 10.1093/qjmed/hcn099
Source DB: PubMed Journal: QJM ISSN: 1460-2393