Literature DB >> 1868346

Phospholipase C isozymes in neurons and glial cells in culture: an immunocytochemical and immunochemical study.

M Mizuguchi1, M Yamada, S U Kim, S G Rhee.   

Abstract

Expression of 3 brain isozymes of phospholipase (PLC-beta, PLC-gamma and PLC-delta) was investigated in relation to cell types found in rat CNS cultures. Immunoreactivity of cultured neurons, astrocytes and oligodendrocytes was demonstrated for all of the 3 isozymes by immunocytochemical staining and immunoblotting, with some differences in reaction intensity. Immunoblotting revealed that the level of expression was neurons greater than oligodendrocytes greater than astrocytes for PLC-beta and PLC-gamma, and astrocytes greater than oligodendrocytes greater than neurons for PLC-delta.

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Year:  1991        PMID： 1868346     DOI： 10.1016/0006-8993(91)91103-8

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

1.  Astrocytic and neuronal localization of the scaffold protein Na+/H+ exchanger regulatory factor 2 (NHERF-2) in mouse brain.

Authors:  Maryse Paquet; Masaaki Kuwajima; C Chris Yun; Yoland Smith; Randy A Hall
Journal:  J Comp Neurol       Date:  2006-02-10       Impact factor: 3.215

2.  PLCγ2 promotes apoptosis while inhibits proliferation in rat hepatocytes through PKCD/JNK MAPK and PKCD/p38 MAPK signalling.

Authors:  Xiaoguang Chen; Qiongxia Lv; Jun Ma; Yumei Liu
Journal:  Cell Prolif       Date:  2018-02-11       Impact factor: 6.831

3.  Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments.

Authors:  Y W Peng; S G Rhee; W P Yu; Y K Ho; T Schoen; G J Chader; K W Yau
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-04       Impact factor: 11.205

4.  High expression of doublecortin and KIAA0369 protein in fetal brain suggests their specific role in neuronal migration.

Authors:  M Mizuguchi; J Qin; M Yamada; K Ikeda; S Takashima
Journal:  Am J Pathol       Date:  1999-11       Impact factor: 4.307

5.  Phospholipases of mineralization competent cells and matrix vesicles: roles in physiological and pathological mineralizations.

Authors:  Saida Mebarek; Abdelkarim Abousalham; David Magne; Le Duy Do; Joanna Bandorowicz-Pikula; Slawomir Pikula; René Buchet
Journal:  Int J Mol Sci       Date:  2013-03-01       Impact factor: 5.923

Review 6.  Phosphoinositide pathway and the signal transduction network in neural development.

Authors:  Vincenza Rita Lo Vasco
Journal:  Neurosci Bull       Date:  2012-11-14       Impact factor: 5.203

7.  Phospholipase C-delta extends intercellular signalling range and responses to injury-released growth factors in non-excitable cells.

Authors:  L Y Mi; D S Ettenson; E R Edelman
Journal:  Cell Prolif       Date:  2008-06-19       Impact factor: 6.831

Review 8.  Emerging roles of PLCγ1 in endothelial biology.

Authors:  Dongying Chen; Michael Simons
Journal:  Sci Signal       Date:  2021-08-03       Impact factor: 8.192

9.  Phospholipase C Beta 1: a Candidate Signature Gene for Proneural Subtype High-Grade Glioma.

Authors:  Guangrong Lu; Jeffrey T Chang; Zheyu Liu; Yong Chen; Min Li; Jay-Jiguang Zhu
Journal:  Mol Neurobiol       Date:  2015-11-28       Impact factor: 5.590
  9 in total

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