Literature DB >> 18682233

TGFbeta and SMADs talk to NANOG in human embryonic stem cells.

Jianming Jiang1, Huck-Hui Ng.   

Abstract

The TGFbeta/activin signaling pathway is important for the maintenance of human embryonic stem cells. In this issue of Cell Stem Cell, Xu et al. (2008) show that this pathway upregulates the expression of a key pluripotency gene NANOG through SMAD2/3.

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Year:  2008        PMID： 18682233     DOI： 10.1016/j.stem.2008.07.011

Source DB:  PubMed          Journal:  Cell Stem Cell        ISSN： 1875-9777            Impact factor:   24.633


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