Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Absence of 5' terminal capping in encephalomyocarditis virus RNA.

Literature DB >> 186763

Absence of 5' terminal capping in encephalomyocarditis virus RNA.

Abstract

The nature of the 5' terminus of encephalomyocarditis (EMC) virion RNA has been investigated. We have failed to detect any capped products or nucleoside polyphosphates arising upon complete digestion of the RNA with T1, T2, and pancreatic ribonucleases, and it would therefore appear that the 5' terminus of EMC virus RNA is not phosphorylated and not capped with m7G. EMC virions do contain, however, large amounts of all four 5'-monosubstituted nucleoside triphosphates (4.2M pppG; 16.4M pppA; 3.OM pppU and 2.5M pppC), of which at least a proportion (about 15-20%) appear to remain bound to fully denatured RNA in the presence of divalent cations.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1976 PMID： 186763 PMCID： PMC343127 DOI： 10.1093/nar/3.10.2771

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

30 in total

1. "Methylation-coupled" transcription by virus-associated transcriptase of cytoplasmic polyhedrosis virus containing double-stranded RNA.

Authors: Y Furuichi
Journal: Nucleic Acids Res Date: 1974-06 Impact factor: 16.971

Absence of 5' terminal capping in encephalomyocarditis virus RNA.

1. "Methylation-coupled" transcription by virus-associated transcriptase of cytoplasmic polyhedrosis virus containing double-stranded RNA.

2. The methylated constituents of L cell messenger RNA: evidence for an unusual cluster at the 5' terminus.

3. A protein binding the methylated 5'-terminal sequence, m7GpppN, of eukaryotic messenger RNA.

4. Inhibition of initiation of protein synthesis by 7-methylguanosine-5'-monophosphate.

5. 5'-Terminal m-7G(5')ppp(5')G-m-p in vivo: identification in reovirus genome RNA.

6. Methylated, blocked 5 termini in HeLa cell mRNA.

7. A modified structure at the 5'-terminus of mRNA of vaccinia virus.

8. mRNA methylation and protein synthesis in extracts from embryos of brine shrimp, Artemia salina.

9. Modified nucleosides and bizarre 5'-termini in mouse myeloma mRNA.

10. Ribosome binding to reovirus mRNA in protein synthesis requires 5' terminal 7-methylguanosine.

1. A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5'-terminal cap in mRNA.

2. Bidirectional RNA helicase activity of eucaryotic translation initiation factors 4A and 4F.

3. Encephalomyocarditis virus RNA. III. Presence of a genome-associated protein.

4. More precise location of the polycytidylic acid tract in foot and mouth disease virus RNA.

5. Inactivation of cap-binding proteins accompanies the shut-off of host protein synthesis by poliovirus.

6. Analysis of terminal structures of RNA from potato virus X.

7. Association of a Mr 50,000 cap-binding protein with the cytoskeleton in baby hamster kidney cells.

8. ATP/Mg++-dependent cross-linking of cap binding proteins to the 5' end of eukaryotic mRNA.

9. In Vitro Replication of Cowpea Mosaic Virus RNA III. Template Recognition by Cowpea Mosaic Virus RNA Replicase.