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Literature DB >> 1057180

Methylated, blocked 5 termini in HeLa cell mRNA.

Y Furuichi, M Morgan, A J Shatkin, W Jelinek, M Salditt-Georgieff, J E Darnell.

Abstract

Poly(A)-containing HeLa cell mRNA prepared from cells labeled with [methyl-(3)H]methionine or [(32)P]phosphate was found to contain a variety of methylated, blocked 5'-terminal structures of two general types: m(7)GpppN(7)-Np and m(7)GpppN(m)-N(m)-Np. In addition, about one-third of the [(3)H]methyl label was present in the N(6)-methyladenosine; this labeled nucleoside was not found in the 3'-terminal one-third of the mRNA chain and thus may also be in the 5' portion of the mRNA.

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Year: 1975 PMID： 1057180 PMCID： PMC432656 DOI： 10.1073/pnas.72.5.1904

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

9 in total

1. "Methylation-coupled" transcription by virus-associated transcriptase of cytoplasmic polyhedrosis virus containing double-stranded RNA.

Authors: Y Furuichi
Journal: Nucleic Acids Res Date: 1974-06 Impact factor: 16.971

2. Insect hormones as tsetse abortifacients.

Authors: D L Denlinger
Journal: Nature Date: 1975-01-31 Impact factor: 49.962

3. Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: m-7G(5')ppp(5')G-MpCp-.

Authors: Y Furuichi; M Morgan; S Muthukrishnan; A J Shatkin
Journal: Proc Natl Acad Sci U S A Date: 1975-01 Impact factor: 11.205

4. 5'-Terminal m-7G(5')ppp(5')G-m-p in vivo: identification in reovirus genome RNA.

Authors: Y Furuichi; S Muthukrishnan; A J Shatkin
Journal: Proc Natl Acad Sci U S A Date: 1975-02 Impact factor: 11.205

5. Methylated nucleotides block 5'-terminus of vaccinia virus messenger RNA.

Authors: C M Wei; B Moss
Journal: Proc Natl Acad Sci U S A Date: 1975-01 Impact factor: 11.205

6. A modified structure at the 5'-terminus of mRNA of vaccinia virus.

Authors: T Urushibara; Y Furuichi; C Nishimura; K Miura
Journal: FEBS Lett Date: 1975-01-01 Impact factor: 4.124

7. Biogenesis of mRNA: genetic regulation in mammalian cells.

Authors: J E Darnell; W R Jelinek; G R Molloy
Journal: Science Date: 1973-09-28 Impact factor: 47.728

8. Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells.

Authors: R Desrosiers; K Friderici; F Rottman
Journal: Proc Natl Acad Sci U S A Date: 1974-10 Impact factor: 11.205

9. Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing.

Authors: F Rottman; A J Shatkin; R P Perry
Journal: Cell Date: 1974-11 Impact factor: 41.582

9 in total

98 in total

10. Poxvirus decapping enzymes enhance virulence by preventing the accumulation of dsRNA and the induction of innate antiviral responses.

Authors: Shin-Wu Liu; George C Katsafanas; Ruikang Liu; Linda S Wyatt; Bernard Moss
Journal: Cell Host Microbe Date: 2015-03-11 Impact factor: 21.023

Methylated, blocked 5 termini in HeLa cell mRNA.

1. "Methylation-coupled" transcription by virus-associated transcriptase of cytoplasmic polyhedrosis virus containing double-stranded RNA.

2. Insect hormones as tsetse abortifacients.

3. Reovirus messenger RNA contains a methylated, blocked 5'-terminal structure: m-7G(5')ppp(5')G-MpCp-.

4. 5'-Terminal m-7G(5')ppp(5')G-m-p in vivo: identification in reovirus genome RNA.

5. Methylated nucleotides block 5'-terminus of vaccinia virus messenger RNA.

6. A modified structure at the 5'-terminus of mRNA of vaccinia virus.

7. Biogenesis of mRNA: genetic regulation in mammalian cells.

8. Identification of methylated nucleosides in messenger RNA from Novikoff hepatoma cells.

9. Sequences containing methylated nucleotides at the 5' termini of messenger RNAs: possible implications for processing.

1. Influenza viral mRNA contains internal N6-methyladenosine and 5'-terminal 7-methylguanosine in cap structures.

2. E.B. Wilson Lecture, 1998. Eukaryotic RNAs: once more from the beginning.

3. Structure of the guanylyltransferase domain of human mRNA capping enzyme.

4. Partial purification of a 6-methyladenine mRNA methyltransferase which modifies internal adenine residues.

5. Sequence specificity of the human mRNA N6-adenosine methylase in vitro.

Review 6. An unconventional pathway of mRNA cap formation by vesiculoviruses.

7. Short-lived methylated messenger RNA in mouse kidney.

8. Very short-lived and stable mRNAs from resting human lymphocytes.

9. Inhibition of initiation of protein synthesis by 7-methylguanosine-5'-monophosphate.

10. Poxvirus decapping enzymes enhance virulence by preventing the accumulation of dsRNA and the induction of innate antiviral responses.