Ralitza Gueorguieva1, Steven B Morse, Jeffrey Roth. 1. Division of Biostatistics, Department of Epidemiology and Public Health, Yale University, 60 College St, Room 201, New Haven, CT 06520-8034, USA. ralitza.gueorguieva@yale.edu
Abstract
OBJECTIVE: To assess the association between length of prenatal participation in WIC and a marker of infant morbidity. By focusing on small for gestational age, we consider one of the possible pathways through which prenatal nutrition affects fetal growth. DESIGN/ METHODS: The study sample consists of 369,535 matched mother-infant pairs drawn from all singleton live births in Florida hospitals from 1996 to 2004. All subjects received WIC and Medicaid-funded prenatal services during pregnancy. We controlled for selection bias on observed variables using a generalized propensity scoring approach and performed separate analyses by gestational age category to control for simultaneity bias. RESULTS: Ten percent increase in the percent of time in WIC was associated with 2.5% decrease (95% CI: 2.1-3.0%) in the risk of a full-term an SGA infant. The risk was also significantly decreased for very preterm and late preterm infants (29-33 and 34-36 weeks gestation) but not for extremely preterm infants (23-28 weeks gestation). CONCLUSIONS: The observed small negative dose response relationship between percent of pregnancy spent in WIC and fetal growth restriction implies that longer participation in the program confers a small measure of protection against delivering an SGA infant.
OBJECTIVE: To assess the association between length of prenatal participation in WIC and a marker of infant morbidity. By focusing on small for gestational age, we consider one of the possible pathways through which prenatal nutrition affects fetal growth. DESIGN/ METHODS: The study sample consists of 369,535 matched mother-infant pairs drawn from all singleton live births in Florida hospitals from 1996 to 2004. All subjects received WIC and Medicaid-funded prenatal services during pregnancy. We controlled for selection bias on observed variables using a generalized propensity scoring approach and performed separate analyses by gestational age category to control for simultaneity bias. RESULTS: Ten percent increase in the percent of time in WIC was associated with 2.5% decrease (95% CI: 2.1-3.0%) in the risk of a full-term an SGA infant. The risk was also significantly decreased for very preterm and late preterm infants (29-33 and 34-36 weeks gestation) but not for extremely preterm infants (23-28 weeks gestation). CONCLUSIONS: The observed small negative dose response relationship between percent of pregnancy spent in WIC and fetal growth restriction implies that longer participation in the program confers a small measure of protection against delivering an SGA infant.
Authors: Anthony M Vintzileos; Cande V Ananth; John C Smulian; William E Scorza; Robert A Knuppel Journal: Am J Obstet Gynecol Date: 2002-11 Impact factor: 8.661
Authors: Marianne M Hillemeier; Marisa E Domino; Rebecca Wells; Ravi K Goyal; Hye-Chung Kum; Dorothy Cilenti; Anirban Basu Journal: Health Serv Res Date: 2017-07-20 Impact factor: 3.402