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Literature DB >> 18652508

Mild and highly efficient method for the synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles.

Kiumars Bahrami¹, M Mehdi Khodaei, Fardin Naali.

Abstract

A new, convenient method for the syntheses of 2-substituted benzimidazole and benzothizole is described. Short reaction times, large-scale synthesis, easy and quick isolation of the products, excellent chemoselectivity, and excellent yields are the main advantages of this procedure.

Entities: Chemical

Mesh：

Substances：

Year: 2008 PMID： 18652508 DOI： 10.1021/jo8010232

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

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Cited

19 in total

1. Thiol dioxygenase turnover yields benzothiazole products from 2-mercaptoaniline and O₂-dependent oxidation of primary alcohols.

Authors: William P Morrow; Sinjinee Sardar; Pawan Thapa; Mohammad S Hossain; Frank W Foss; Brad S Pierce
Journal: Arch Biochem Biophys Date: 2017-08-18 Impact factor: 4.013

2. Oxidative condensations to form benzimidazole-substituted potassium organotrifluoroborates.

Authors: Gary A Molander; Kehinde Ajayi
Journal: Org Lett Date: 2012-08-08 Impact factor: 6.005

3. Enantioselective C2-Allylation of Benzimidazoles Using 1,3-Diene Pronucleophiles.

Authors: James Levi Knippel; Yuxuan Ye; Stephen L Buchwald
Journal: Org Lett Date: 2021-03-01 Impact factor: 6.005

4. 2-(Thio-phen-2-yl)-1-(thio-phen-2-ylmeth-yl)-1H-benzimidazole.

Authors: David K Geiger; H Cristina Geiger; Leo Williams; Bruce C Noll
Journal: Acta Crystallogr Sect E Struct Rep Online Date: 2012-01-18

5. A simple, efficient synthesis of 2-aryl benzimidazoles using silica supported periodic Acid catalyst and evaluation of anticancer activity.

Authors: Vyankat A Sontakke; Sougata Ghosh; Pravin P Lawande; Balu A Chopade; Vaishali S Shinde
Journal: ISRN Org Chem Date: 2013-04-24

6. Structure-based design of functionalized 2-substituted and 1,2-disubstituted benzimidazole derivatives and their in vitro antibacterial efficacy.

Authors: Olayinka O Ajani; Olayinka O Tolu-Bolaji; Shade J Olorunshola; Yuxia Zhao; Damilola V Aderohunmu
Journal: J Adv Res Date: 2017-09-22 Impact factor: 10.479

Mild and highly efficient method for the synthesis of 2-arylbenzimidazoles and 2-arylbenzothiazoles.

1. Thiol dioxygenase turnover yields benzothiazole products from 2-mercaptoaniline and O₂-dependent oxidation of primary alcohols.

2. Oxidative condensations to form benzimidazole-substituted potassium organotrifluoroborates.

3. Enantioselective C2-Allylation of Benzimidazoles Using 1,3-Diene Pronucleophiles.

4. 2-(Thio-phen-2-yl)-1-(thio-phen-2-ylmeth-yl)-1H-benzimidazole.

5. A simple, efficient synthesis of 2-aryl benzimidazoles using silica supported periodic Acid catalyst and evaluation of anticancer activity.

6. Structure-based design of functionalized 2-substituted and 1,2-disubstituted benzimidazole derivatives and their in vitro antibacterial efficacy.

7. Synthesis and Spectroscopic Analysis of Novel 1H-Benzo[d]imidazoles Phenyl Sulfonylpiperazines.

8. Facile and efficient one-pot synthesis of benzimidazoles using lanthanum chloride.

9. Benzimidazole-1,2,3-triazole hybrid molecules: synthesis and evaluation for antibacterial/antifungal activity.

10. An Efficient Greener Approach for N-Acylation of Amines in Water Using Benzotriazole Chemistry.