Candidemia in the 21st century.

The 21st century has brought forth vast innovations in the healthcare field. The availability and use of aggressive chemotherapeutic and immunosuppressive agents as well as broad-spectrum antibacterial agents has created a large population of patients who are at increased risk of acquiring infections with fungal organisms, especially Candida species. This review will focus on the changing epidemiology of candidal bloodstream infections, its impact on healthcare and new advances in the diagnosis and treatment of candidemia.