Literature DB >> 18651117

[Acute coronary syndrome in the elderly. Optimal revascularisation strategies].

M H Wehr1.   

Abstract

Although there are accepted guidelines for treatment of acute coronary syndromes and ST-segment elevation myocardial infarction, elderly patients may have a variety of conditions that can complicate the decision making process about the best therapy. For fear of adverse effects many elderly patients do not receive potentially lifesaving treatments, such as percutaneous coronary intervention or thrombolytic therapy. Appropriate revascularisation therapy also often will be received too late in the course of the infarct, when irreversible myocardial damage has occurred. Many studies, however, show that older patients will benefit substantially from these therapies and early treatment improves outcome in this population, despite a higher risk of complications. In this review, the evidence regarding medical and revascularisation therapies in acute coronary syndromes in the elderly is critically examined.

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Year:  2008        PMID: 18651117     DOI: 10.1007/s00108-008-2078-z

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN: 0020-9554            Impact factor:   0.743


  26 in total

1.  Thrombolytic therapy in older patients.

Authors:  A K Berger; M J Radford; Y Wang; H M Krumholz
Journal:  J Am Coll Cardiol       Date:  2000-08       Impact factor: 24.094

Review 2.  Facilitated percutaneous coronary intervention.

Authors:  William B Borden; David P Faxon
Journal:  J Am Coll Cardiol       Date:  2006-08-28       Impact factor: 24.094

3.  Age-related trends in short- and long-term survival after acute myocardial infarction: a 20-year population-based perspective (1975-1995).

Authors:  R J Goldberg; D McCormick; J H Gurwitz; J Yarzebski; D Lessard; J M Gore
Journal:  Am J Cardiol       Date:  1998-12-01       Impact factor: 2.778

Review 4.  Pharmacological facilitation of primary percutaneous coronary intervention for acute myocardial infarction: is the slope of the curve the shape of the future?

Authors:  Bernard J Gersh; Gregg W Stone; Harvey D White; David R Holmes
Journal:  JAMA       Date:  2005-02-23       Impact factor: 56.272

5.  Representation of elderly persons and women in published randomized trials of acute coronary syndromes.

Authors:  P Y Lee; K P Alexander; B G Hammill; S K Pasquali; E D Peterson
Journal:  JAMA       Date:  2001-08-08       Impact factor: 56.272

6.  Comparison of primary coronary angioplasty and intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review.

Authors:  W D Weaver; R J Simes; A Betriu; C L Grines; F Zijlstra; E Garcia; L Grinfeld; R J Gibbons; E E Ribeiro; M A DeWood; F Ribichini
Journal:  JAMA       Date:  1997-12-17       Impact factor: 56.272

7.  Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: the GUSTO V randomised trial.

Authors:  E J Topol
Journal:  Lancet       Date:  2001-06-16       Impact factor: 79.321

8.  Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes.

Authors:  Karen P Alexander; Anita Y Chen; Matthew T Roe; L Kristin Newby; C Michael Gibson; Nancy M Allen-LaPointe; Charles Pollack; W Brian Gibler; E Magnus Ohman; Eric D Peterson
Journal:  JAMA       Date:  2005-12-28       Impact factor: 56.272

9.  A comparison of immediate angioplasty with thrombolytic therapy for acute myocardial infarction. The Primary Angioplasty in Myocardial Infarction Study Group.

Authors:  C L Grines; K F Browne; J Marco; D Rothbaum; G W Stone; J O'Keefe; P Overlie; B Donohue; N Chelliah; G C Timmis
Journal:  N Engl J Med       Date:  1993-03-11       Impact factor: 91.245

10.  Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric Cardiology.

Authors:  Karen P Alexander; L Kristin Newby; Paul W Armstrong; Christopher P Cannon; W Brian Gibler; Michael W Rich; Frans Van de Werf; Harvey D White; W Douglas Weaver; Mary D Naylor; Joel M Gore; Harlan M Krumholz; E Magnus Ohman
Journal:  Circulation       Date:  2007-05-15       Impact factor: 29.690

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