OBJECTIVE: The aim of the present study was to assess the factors affecting collateral vessel development in patients with acute myocardial infarction. METHODS AND RESULTS: Between May 2001 and April 2004, coronary angiography was performed on 74 patients following myocardial infarction. Only patients with total proximal occlusion in the left anterior descending coronary artery (LAD) or right coronary artery (RCA) in angiography were included in the study. Patients were separated into two groups according to the development of coronary collateral circulation (CCC). In group 1, CCC was inadequate (Rentrop 0, 1 and 2); and in group 2, CCC was adequate (Rentrop 3). Although CCC was adequate in 20 of 28 (71%) patients who had RCA occlusion (P=0.015), it was adequate in only 14 of 46 (30%) patients who had LAD occlusion (P>0.05). The presence of angina pectoris was positively correlated with the development of CCC (P=0.03). Diabetes mellitus (DM) was present in 14 of 40 (35%) patients with inadequate CCC and four of 34 (11%) patients with adequate CCC. The presence of DM was significantly higher in the group with inadequate development of CCC (P=0.017). CONCLUSIONS: While DM was associated with an inadequate development of CCC, the presence of angina pectoris and RCA occlusion were associated with an adequate development of CCC.
OBJECTIVE: The aim of the present study was to assess the factors affecting collateral vessel development in patients with acute myocardial infarction. METHODS AND RESULTS: Between May 2001 and April 2004, coronary angiography was performed on 74 patients following myocardial infarction. Only patients with total proximal occlusion in the left anterior descending coronary artery (LAD) or right coronary artery (RCA) in angiography were included in the study. Patients were separated into two groups according to the development of coronary collateral circulation (CCC). In group 1, CCC was inadequate (Rentrop 0, 1 and 2); and in group 2, CCC was adequate (Rentrop 3). Although CCC was adequate in 20 of 28 (71%) patients who had RCA occlusion (P=0.015), it was adequate in only 14 of 46 (30%) patients who had LAD occlusion (P>0.05). The presence of angina pectoris was positively correlated with the development of CCC (P=0.03). Diabetes mellitus (DM) was present in 14 of 40 (35%) patients with inadequate CCC and four of 34 (11%) patients with adequate CCC. The presence of DM was significantly higher in the group with inadequate development of CCC (P=0.017). CONCLUSIONS: While DM was associated with an inadequate development of CCC, the presence of angina pectoris and RCA occlusion were associated with an adequate development of CCC.
Authors: C W Lee; S W Park; G Y Cho; M K Hong; J J Kim; D H Kang; J K Song; H J Lee; S J Park Journal: J Am Coll Cardiol Date: 2000-03-15 Impact factor: 24.094
Authors: Zhi Liu; Margaret A Pericak-Vance; Pascal Goldschmidt-Clermont; David Seo; Liyong Wang; Tatjana Rundek; Gary W Beecham Journal: PLoS One Date: 2017-10-10 Impact factor: 3.240