Literature DB >> 18649015

The Starbuck stops here: it's a Smad world.

Andrew Leask1.   

Abstract

A recent study by Gressner and colleagues suggested caffeine may block CCN2 expression in hepatic cells. This commentary briefly summarizes these observations.

Entities:  

Year:  2008        PMID： 18649015      PMCID： PMC2570008          DOI： 10.1007/s12079-008-0025-3

Source DB:  PubMed          Journal:  J Cell Commun Signal        ISSN： 1873-9601            Impact factor:   5.782


  4 in total

1.  Coffee and tea consumption are associated with a lower incidence of chronic liver disease in the United States.

Authors:  Constance E Ruhl; James E Everhart
Journal:  Gastroenterology       Date:  2005-12       Impact factor: 22.682

2.  CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling.

Authors:  A Holmes; D J Abraham; S Sa; X Shiwen; C M Black; A Leask
Journal:  J Biol Chem       Date:  2001-01-04       Impact factor: 5.157

Review 3.  TGF-beta signaling and the fibrotic response.

Authors:  Andrew Leask; David J Abraham
Journal:  FASEB J       Date:  2004-05       Impact factor: 5.191

4.  Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways.

Authors:  Olav A Gressner; Birgit Lahme; Katharina Rehbein; Monika Siluschek; Ralf Weiskirchen; Axel M Gressner
Journal:  J Hepatol       Date:  2008-04-30       Impact factor: 25.083
  4 in total
  2 in total

1.  Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

Authors:  Andrew Leask; Sunil K Parapuram; Xu Shi-Wen; D J Abraham
Journal:  J Cell Commun Signal       Date:  2009-01-21       Impact factor: 5.782

2.  Strategies for blocking the fibrogenic actions of connective tissue growth factor (CCN2): From pharmacological inhibition in vitro to targeted siRNA therapy in vivo.

Authors:  David R Brigstock
Journal:  J Cell Commun Signal       Date:  2009-03-18       Impact factor: 5.782
  2 in total

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