Literature DB >> 18648929

A male phenotype (XY) hermaphrodite treated for seminoma, fathered a healthy child by IVF-ICSI technique.

Faheem Zayed1, Ibrahim Ghalayini, Ismail Matalka.   

Abstract

OBJECTIVE: To report a successful delivery of a healthy infant fathered by an infertile 46, XY true hermaphrodite who suffered from a seminoma.
DESIGN: Case report
SETTING: IVF unit in University hospital. PATIENT(S): Male 41 years (true hermaphrodite), his wife 35 years. MAIN OUTCOME MEASURES: Laboratory, pathology tests and ultrasound tests.
RESULTS: The above patient treated and cured from seminoma, the couple had in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) using frozen testicular sperm and had a healthy baby.
CONCLUSION: This is the first case report of a successful delivery of a healthy infant fathered by an infertile 46, XY true hermaphrodite who suffered from a seminoma. Once treated and cured, the couple had IVF and ICSI using frozen testicular sperm and had a healthy baby.

Entities:  

Mesh:

Year:  2008        PMID: 18648929      PMCID: PMC2596674          DOI: 10.1007/s10815-008-9234-1

Source DB:  PubMed          Journal:  J Assist Reprod Genet        ISSN: 1058-0468            Impact factor:   3.412


  17 in total

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2.  Testicular sperm extraction in cancerous testicle in patients with azoospermia: a case report.

Authors:  Luca Carmignani; Franco Gadda; Giacomo Gazzano; Guido Ragni; Alessio Paffoni; Francesco Rocco; Giovanni Maria Colpi
Journal:  Hum Reprod       Date:  2006-12-15       Impact factor: 6.918

3.  Birth after treatment of a male with seminoma and azoospermia with cryopreserved-thawed testicular tissue.

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Journal:  Hum Reprod       Date:  2000-04       Impact factor: 6.918

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Journal:  Hum Reprod       Date:  1997-04       Impact factor: 6.918

5.  Testicular sperm extraction in a patient with metachronous bilateral testicular cancer.

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Journal:  Hum Reprod       Date:  2001-11       Impact factor: 6.918

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Journal:  Urology       Date:  1994-04       Impact factor: 2.649

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Authors:  G Krob; A Braun; U Kuhnle
Journal:  Eur J Pediatr       Date:  1994-01       Impact factor: 3.183

10.  Seminoma discovered in two males undergoing successful testicular sperm extraction for intracytoplasmic sperm injection.

Authors:  V Novero; A Goossens; H Tournaye; S Silber; A C Van Steirteghem; P Devroey
Journal:  Fertil Steril       Date:  1996-05       Impact factor: 7.329

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  1 in total

1.  Successful second delivery outcome using refrozen thawed testicular sperm from an infertile male true hermaphrodite with a 46, XX/46, XY karyotype: case report.

Authors:  Nobuo Sugawara; Yasuyuki Kimura; Yasuhisa Araki
Journal:  Hum Cell       Date:  2012-12-01       Impact factor: 4.174

  1 in total

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