Literature DB >> 18633671

Entirely laparoscopic radical gastrectomy for adenocarcinoma: lymph node yield and resection margins.

Abeezar I Sarela1.   

Abstract

BACKGROUND: Laparoscopic assisted distal gastrectomy for adenocarcinoma has been widely reported from Japan and Korea but there are sparse data for Western patients. This study aimed to describe and compare the perioperative outcomes and pathological staging for consecutive patients who underwent laparoscopic or open gastrectomy by a single surgeon in the UK.
METHODS: During the period from April 2005 to May, 2007, patients with gastric adenocarcinoma were selected for open or laparoscopic resection at the discretion of the surgeon. Gastric resections for gastrointestinal stromal tumour (GIST) or benign disease were excluded. Laparoscopic gastrectomy was performed entirely laparoscopically with intracorporeal anastomosis, followed by specimen retrieval via a suprapubic incision.
RESULTS: There were 21 men and 8 women, median age 75 years (range 45-88 years), with American Anaesthesiology Association scores of 3 or 4 in 19 patients. Gastrectomy was performed laparoscopically in 18 patients (62%; total gastrectomy, 6 patients) or open in 11 patients (total gastrectomy, 7). Five laparoscopic gastrectomies were converted to open procedures, three patients had re-laparoscopy and one patient had subsequent laparotomy. As compared with open gastrectomy, laparoscopic resection had longer operation time and similar length of hospital stay. There was one postoperative mortality in each group. There was similar lymph node retrieval for laparoscopic or open resection [23 (range 10-44) versus 26 (8-95), respectively; p = 0.40], with inadequate lymphadenectomy (<15 nodes) in two laparoscopic cases and one open case. R1 resection was limited to patients with pT3 disease (laparoscopic, 4; open, 2).
CONCLUSIONS: Perioperative outcomes were similar for laparoscopic or open gastrectomy. Lymphadenectomy was adequate in 89% of laparoscopic gastrectomies. pT3 tumours were at risk of noncurative resection, as described in large Western series of open gastrectomy.

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Year:  2008        PMID: 18633671     DOI: 10.1007/s00464-008-0072-0

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  30 in total

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3.  Clinical outcomes with laparoscopic stage M1, unresected gastric adenocarcinoma.

Authors:  Abeezar I Sarela; Thomas J Miner; Martin S Karpeh; Daniel G Coit; David P Jaques; Murray F Brennan
Journal:  Ann Surg       Date:  2006-02       Impact factor: 12.969

4.  Laparoscopic surgery for gastric cancer: preliminary experience.

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Journal:  Gastric Cancer       Date:  2005       Impact factor: 7.370

5.  Short-term endpoints of conventional versus laparoscopic-assisted surgery in patients with colorectal cancer (MRC CLASICC trial): multicentre, randomised controlled trial.

Authors:  Pierre J Guillou; Philip Quirke; Helen Thorpe; Joanne Walker; David G Jayne; Adrian M H Smith; Richard M Heath; Julia M Brown
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  12 in total

1.  Laparoscopic versus open distal gastrectomy for locally advanced gastric cancer: a case-control study.

Authors:  Marco Scatizzi; Katrin C Kröning; Elisa Lenzi; Luca Moraldi; Stefano Cantafio; Francesco Feroci
Journal:  Updates Surg       Date:  2011-02-01

2.  Laparoscopic gastrectomy for organ-confined cancer: a reality in the West?

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10.  Randomized Trial of Immediate Postoperative Pain Following Single-incision Versus Traditional Laparoscopic Cholecystectomy.

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