Literature DB >> 18632906

Genetic lineages of community-associated methicillin-resistant Staphylococcus aureus in Kuwait hospitals.

E E Udo1, F G O'Brien, N Al-Sweih, Bobby Noronha, B Matthew, W B Grubb.   

Abstract

Twenty-six community-associated methicillin-resistant Staphylococcus aureus (CAMSRA) isolates were characterized by pulsed-field gel electrophoresis (PFGE) and multilocus sequence typing (MLST) and screened for accessory gene regulator (agr), capsular polysaccharide (cap), and Panton-Valentine leucocidin (PVL) genes. They exhibited five PFGE patterns (types A to E). The majority were PFGE type A (12 isolates) or type B (8 isolates). MLST showed that PFGE type A isolates belonged to sequence type 80 (ST80), while the PFGE type B isolates were ST30. The ST80 and ST30 clones contained agr allotype 3, cap type 8, and PVL. The results showed that two internationally recognized CAMRSA clones are dominant in Kuwait hospitals.

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Year:  2008        PMID： 18632906      PMCID： PMC2566081          DOI： 10.1128/JCM.00966-08

Source DB:  PubMed          Journal:  J Clin Microbiol        ISSN： 0095-1137            Impact factor:   5.948


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