Literature DB >> 18623181

Microbial production of (+)-trans-isochorismic acid.

K Schmidt1, E Leistner.   

Abstract

Two methods are described for the preparation of enantiomerically pure (+)-trans-isochorismic acid, an important metabolite of the postchorismate pathway. Both methods can be employed to prepare isotopically labeled isochorismic acid. One of the two methods is suitable to prepare bulk quantities of isochorismic acid using a recombinant strain of Klebsiella pneumoniae 62-1. (c) 1995 John Wiley & Sons, Inc.

Entities:  

Year:  1995        PMID： 18623181     DOI： 10.1002/bit.260450402

Source DB:  PubMed          Journal:  Biotechnol Bioeng        ISSN： 0006-3592            Impact factor:   4.530


  7 in total

1.  pH Dependence of catalysis by Pseudomonas aeruginosa isochorismate-pyruvate lyase: implications for transition state stabilization and the role of lysine 42.

Authors:  Jose Olucha; Andrew N Ouellette; Qianyi Luo; Audrey L Lamb
Journal:  Biochemistry       Date:  2011-07-22       Impact factor: 3.162

2.  Expanding the results of a high throughput screen against an isochorismate-pyruvate lyase to enzymes of a similar scaffold or mechanism.

Authors:  Kathleen M Meneely; Qianyi Luo; Andrew P Riley; Byron Taylor; Anuradha Roy; Ross L Stein; Thomas E Prisinzano; Audrey L Lamb
Journal:  Bioorg Med Chem       Date:  2014-09-16       Impact factor: 3.641

3.  Redesign of MST enzymes to target lyase activity instead promotes mutase and dehydratase activities.

Authors:  Kathleen M Meneely; Qianyi Luo; Audrey L Lamb
Journal:  Arch Biochem Biophys       Date:  2013-09-19       Impact factor: 4.013

4.  Entropic and enthalpic components of catalysis in the mutase and lyase activities of Pseudomonas aeruginosa PchB.

Authors:  Qianyi Luo; Kathleen M Meneely; Audrey L Lamb
Journal:  J Am Chem Soc       Date:  2011-04-19       Impact factor: 15.419

5.  Microbial production of specifically ring-13C-labelled 4-hydroxybenzoic acid.

Authors:  R Müller; A Wagener; K Schmidt; E Leistner
Journal:  Appl Microbiol Biotechnol       Date:  1995-11       Impact factor: 4.813

6.  Lysine221 is the general base residue of the isochorismate synthase from Pseudomonas aeruginosa (PchA) in a reaction that is diffusion limited.

Authors:  Kathleen M Meneely; Qianyi Luo; Prajnaparamita Dhar; Audrey L Lamb
Journal:  Arch Biochem Biophys       Date:  2013-08-11       Impact factor: 4.013

7.  An Open and Shut Case: The Interaction of Magnesium with MST Enzymes.

Authors:  Kathleen M Meneely; Jesse A Sundlov; Andrew M Gulick; Graham R Moran; Audrey L Lamb
Journal:  J Am Chem Soc       Date:  2016-07-19       Impact factor: 15.419
  7 in total

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