Literature DB >> 18622540

Results of a new method to stop acute bleeding from esophageal varices: implantation of a self-expanding stent.

J Zehetner1, A Shamiyeh, W Wayand, R Hubmann.   

Abstract

BACKGROUND: Acute bleeding from nontreated esophageal varices is associated with a mortality rate of 30% to 50%. Various pharmacologic and interventional methods to stop acute bleeding are available. However, for 10% to 20% of patients, therapy fails to stop the bleeding. This study aimed to assess the SX-ELLA Stent Danis Set (which has a self-expanding metal stent) instead of a balloon probe for compression of esophageal varices.
METHODS: Using a multidisciplinary approach, a self-expanding stent was placed in 39 patients between January 2003 and August 2007. For 34 of these patients with ongoing bleeding from esophageal varices, stent implantation was performed with the SX-ELLA Stent Danis Set, and the patients were included in this study. For all these patients, common methods failed to stop hemorrhage. With the SX-ELLA Stent Danis Set, the stent was implanted with a positioning balloon that enabled delivery without X-ray control. After implantation of the stent, its position was controlled by endoscopy and computed tomography (CT) scan.
RESULTS: For all 34 patients, the implantation of the esophageal stent succeeded in stopping ongoing bleeding. No stent-related complications occurred during or after stent implantation. No bleeding recurrence was observed during the stent implantation (median time, 5 days; range 1-14 days). For all the patients, the stent could be extracted by endoscopy without any complications using an extractor. Nine patients died of hepatic failure within 30 days after the procedure. No rebleeding occurred.
CONCLUSIONS: The use of a self-expanding stent to stop acute bleeding from esophageal varices is a new therapeutic method. The authors' initial experience, which involved no method-related mortality or complications, is encouraging. More data are necessary to confirm their results.

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Year:  2008        PMID: 18622540     DOI: 10.1007/s00464-008-0009-7

Source DB:  PubMed          Journal:  Surg Endosc        ISSN: 0930-2794            Impact factor:   4.584


  20 in total

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2.  Evaluation of endoscopic variceal ligation (EVL) versus propanolol plus isosorbide mononitrate/nadolol (ISMN) in the prevention of variceal rebleeding: comparison of cirrhotic and noncirrhotic patients.

Authors:  Shiv K Sarin; Manav Wadhawan; Rajesh Gupta; Hansa Shahi
Journal:  Dig Dis Sci       Date:  2005-08       Impact factor: 3.199

3.  Combination endoscopic band ligation and sclerotherapy compared with endoscopic band ligation alone for the secondary prophylaxis of esophageal variceal hemorrhage: a meta-analysis.

Authors:  Hetal A Karsan; Sally C Morton; Paul G Shekelle; Brennan M R Spiegel; Marika J Suttorp; Marc A Edelstein; Ian M Gralnek
Journal:  Dig Dis Sci       Date:  2005-02       Impact factor: 3.199

4.  Evolving consensus in portal hypertension. Report of the Baveno IV consensus workshop on methodology of diagnosis and therapy in portal hypertension.

Authors:  Roberto de Franchis
Journal:  J Hepatol       Date:  2005-07       Impact factor: 25.083

5.  A modified percutaneous transhepatic variceal embolization with 2-octyl cyanoacrylate versus endoscopic ligation in esophageal variceal bleeding management: randomized controlled trial.

Authors:  Chun Qing Zhang; Fu Li Liu; Bo Liang; Zi Qin Sun; Hong Wei Xu; Lin Xu; Kai Feng; Zun Chang Liu
Journal:  Dig Dis Sci       Date:  2007-11-21       Impact factor: 3.199

6.  The use of self-expanding metal stents to treat acute esophageal variceal bleeding.

Authors:  R Hubmann; G Bodlaj; M Czompo; L Benkö; P Pichler; S Al-Kathib; P Kiblböck; A Shamyieh; G Biesenbach
Journal:  Endoscopy       Date:  2006-09       Impact factor: 10.093

Review 7.  Self-expanding metal stents for gastroduodenal malignancies: systematic review of their clinical effectiveness.

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Journal:  Endoscopy       Date:  2004-06       Impact factor: 10.093

8.  An assessment of the management of acute bleeding varices: a multicenter prospective member-based study.

Authors:  Darius Sorbi; Christopher J Gostout; David Peura; David Johnson; Frank Lanza; P Gregory Foutch; Cathy D Schleck; Alan R Zinsmeister
Journal:  Am J Gastroenterol       Date:  2003-11       Impact factor: 10.864

9.  A prospective, randomized controlled trial of transjugular intrahepatic portosystemic shunt versus cyanoacrylate injection in the prevention of gastric variceal rebleeding.

Authors:  G-H Lo; H-L Liang; W-C Chen; M-H Chen; K-H Lai; P-I Hsu; C-K Lin; H-H Chan; H-B Pan
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10.  Novel technique of laparoscopic azygoportal disconnection for treatment of esophageal varicosis: preliminary experience with five patients.

Authors:  J Danis; R Hubmann; P Pichler; A Shamiyeh; W U Wayand
Journal:  Surg Endosc       Date:  2004-03-19       Impact factor: 4.584

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  33 in total

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Journal:  Internist (Berl)       Date:  2010-09       Impact factor: 0.743

2.  Current Management Strategies for Acute Esophageal Variceal Hemorrhage.

Authors:  Brett Fortune; Guadalupe Garcia-Tsao
Journal:  Curr Hepatol Rep       Date:  2014-03-01

3.  Refractory bleeding from a malignant duodenal ulcer treated with placement of a fully-covered gastroduodenal stent.

Authors:  Pernilla M D'Souza; Gurpal S Sandha; Christopher W Teshima
Journal:  Dig Dis Sci       Date:  2013-05-05       Impact factor: 3.199

Review 4.  Historical overview and review of current day treatment in the management of acute variceal haemorrhage.

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Journal:  World J Gastroenterol       Date:  2014-06-07       Impact factor: 5.742

5.  Use of self-expanding metal stents for difficult variceal bleed.

Authors:  M K Goenka; Usha Goenka; I K Tiwary; Vijay Rai
Journal:  Indian J Gastroenterol       Date:  2018-01-24

Review 6.  Update of endoscopy in liver disease: more than just treating varices.

Authors:  Christoforos Krystallis; Gail S Masterton; Peter C Hayes; John N Plevris
Journal:  World J Gastroenterol       Date:  2012-02-07       Impact factor: 5.742

7.  SX-Ella Stent Danis Effectively Controls Refractory Variceal Bleed in Patients with Acute-on-Chronic Liver Failure.

Authors:  Rakhi Maiwall; Kapil Dev Jamwal; Ankit Bhardwaj; Ajeet Singh Bhadoria; Jaswinder Singh Maras; Guresh Kumar; Ankur Jindal; Ashok Choudhury; Lovkesh Anand; Amrish Sahney; Awinash Kumar; Manoj Kumar Sharma; Barjesh Chander Sharma; Shiv Kumar Sarin
Journal:  Dig Dis Sci       Date:  2017-08-05       Impact factor: 3.199

Review 8.  New and emerging endoscopic haemostasis techniques.

Authors:  Rebecca Palmer; Barbara Braden
Journal:  Frontline Gastroenterol       Date:  2015-01-23

Review 9.  Management of varices in patients with cirrhosis.

Authors:  Julia O'Brien; Christos Triantos; Andrew K Burroughs
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2013-04-02       Impact factor: 46.802

Review 10.  Portal hypertension and gastrointestinal bleeding: diagnosis, prevention and management.

Authors:  Erwin Biecker
Journal:  World J Gastroenterol       Date:  2013-08-21       Impact factor: 5.742

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