Literature DB >> 18614319

Point-of-care testing at triage decreases time to lactate level in septic patients.

Munish Goyal1, Jesse M Pines, Byron C Drumheller, David F Gaieski.   

Abstract

Early recognition of elevated lactate levels may hasten the detection of time-sensitive illness. We studied a method to measure lactate levels in septic patients using a point-of-care (POC) device at Emergency Department triage. A convenience sample of adult patients with sepsis was enrolled. Consenting patients received a fingertip lactate measurement using a POC device. Treating clinicians were blinded to study and POC test results. Whole blood lactate levels were drawn at the discretion of the treating physician. A total of 238 patients were eligible; 154 (65%) consented, 5 left without treatment after consenting. Of the remaining 149, 44 (30%) patients received both POC and whole blood lactates. Median time from triage to POC lactate result was 21 min (interquartile range [IQR] 14-25). Median time from triage to whole blood lactate result was 172 min (IQR 119-256). The time difference between POC test result and whole blood lactate result was 151 min (IQR 101-247). Triage POC fingertip lactate is a feasible method for reducing time to identification of lactate levels in patients with sepsis. Larger studies are needed to determine the ability of POC lactate measurement to aid in the risk stratification of septic patients. Copyright 2010 Elsevier Inc. All rights reserved.

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Year:  2008        PMID: 18614319     DOI: 10.1016/j.jemermed.2007.11.099

Source DB:  PubMed          Journal:  J Emerg Med        ISSN: 0736-4679            Impact factor:   1.484


  19 in total

1.  Severe sepsis in pre-hospital emergency care: analysis of incidence, care, and outcome.

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2.  Out-of-hospital characteristics and care of patients with severe sepsis: a cohort study.

Authors:  Christopher W Seymour; Roger A Band; Colin R Cooke; Mark E Mikkelsen; Julie Hylton; Tom D Rea; Christopher H Goss; David F Gaieski
Journal:  J Crit Care       Date:  2010-04-08       Impact factor: 3.425

3.  Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications.

Authors:  Marilyn J Crain; Paige L Williams; Ray Griner; Katherine Tassiopoulos; Jennifer S Read; Lynne M Mofenson; Kenneth C Rich
Journal:  Pediatr Infect Dis J       Date:  2011-12       Impact factor: 2.129

Review 4.  Evidence-based diagnostics: adult septic arthritis.

Authors:  Christopher R Carpenter; Jeremiah D Schuur; Worth W Everett; Jesse M Pines
Journal:  Acad Emerg Med       Date:  2011-08       Impact factor: 3.451

5.  Opportunities for Emergency Medical Services care of sepsis.

Authors:  Henry E Wang; Matthew D Weaver; Nathan I Shapiro; Donald M Yealy
Journal:  Resuscitation       Date:  2009-12-16       Impact factor: 5.262

6.  The feasibility and accuracy of point-of-care lactate measurement in emergency department patients with suspected infection.

Authors:  Nathan I Shapiro; Christopher Fisher; Michael Donnino; Lauren Cataldo; Aimee Tang; Stephen Trzeciak; Gary Horowitz; Richard E Wolfe
Journal:  J Emerg Med       Date:  2009-08-31       Impact factor: 1.484

7.  Portable lactate analyzer for measuring lactate in cerebrospinal fluid (CSF) and plasma - method-comparison evaluations.

Authors:  Sérgio Monteiro de Almeida; Jennifer Marquie-Beck; Archana Bhatt; Scott Letendre; Allen McCutchan; Ron Ellis
Journal:  Arq Neuropsiquiatr       Date:  2014-07       Impact factor: 1.420

8.  Failure to clear elevated lactate predicts 24-hour mortality in trauma patients.

Authors:  Zachary D W Dezman; Angela C Comer; Gordon S Smith; Mayur Narayan; Thomas M Scalea; Jon Mark Hirshon
Journal:  J Trauma Acute Care Surg       Date:  2015-10       Impact factor: 3.313

9.  Cost-effectiveness analysis of early point-of-care lactate testing in the emergency department.

Authors:  Michael J Ward; Wesley H Self; Adam Singer; Danielle Lazar; Jesse M Pines
Journal:  J Crit Care       Date:  2016-07-07       Impact factor: 3.425

10.  Alcohol consumption decreases lactate clearance in acutely injured patients.

Authors:  Zachary D W Dezman; Angela C Comer; Mayur Narayan; Thomas M Scalea; Jon Mark Hirshon; Gordon S Smith
Journal:  Injury       Date:  2016-03-22       Impact factor: 2.586

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