Literature DB >> 18613319

A randomized trial of a breast/ovarian cancer genetic testing decision aid used as a communication aid during genetic counseling.

Claire E Wakefield1, Bettina Meiser, Judi Homewood, Alan Taylor, Margaret Gleeson, Rachel Williams, Kathy Tucker.   

Abstract

OBJECTIVES: To evaluate the impact of a decision aid for women considering genetic testing for breast/ovarian cancer risk given during genetic counseling.
METHODS: One hundred and forty-eight women were randomized to receive the decision aid or a control pamphlet at the beginning of their first consultation with a genetic counselor. When the patient received the decision aid, it was used to complement consultation discussions about genetic testing. One hundred and ten (74.3%) women completed the first questionnaire designed to elicit information about women's levels of decisional conflict and knowledge about genetic testing. Of these, 105 (70.9%) completed a second questionnaire to assess longer-term outcomes, 6 months postconsultation.
RESULTS: Results showed that women who received the decision aid felt more informed about genetic testing (chi(2)(1)=8.69; P=0.003), had clearer values (chi(2)(1)=6.90; P=0.009) and had higher knowledge levels (chi(2)(2)=6.49; P=0.039) than women who received the control pamphlet.
CONCLUSIONS: The developed decision aid improved patient outcomes better than a control pamphlet when implemented during genetic counseling and given to the patient to take home.

Entities:  

Mesh:

Year:  2008        PMID: 18613319     DOI: 10.1002/pon.1353

Source DB:  PubMed          Journal:  Psychooncology        ISSN: 1057-9249            Impact factor:   3.894


  21 in total

1.  Development of Breast Cancer Choices: a decision support tool for young women with breast cancer deciding whether to have genetic testing for BRCA1/2 mutations.

Authors:  Chloe Grimmett; Charlotte Brooks; Alejandra Recio-Saucedo; Anne Armstrong; Ramsey I Cutress; D Gareth Evans; Ellen Copson; Lesley Turner; Bettina Meiser; Claire E Wakefield; Diana Eccles; Claire Foster
Journal:  Support Care Cancer       Date:  2018-06-28       Impact factor: 3.603

Review 2.  Patient responses to genetic information: studies of patients with hereditary cancer syndromes identify issues for use of genetic testing in nephrology practice.

Authors:  Kimberly A Kaphingst; Colleen M McBride
Journal:  Semin Nephrol       Date:  2010-03       Impact factor: 5.299

3.  Factors associated with an individuals' decision to withdraw from genetic counseling for BRCA1 and BRCA2 genes mutations: are personality traits involved?

Authors:  Anita Caruso; Cristina Vigna; Valentina Bigazzi; Carlo Leone; Gabriella Maggi; Aline Martayan; Fabio M Sega; Francesco Cognetti; Antonella Savarese
Journal:  Fam Cancer       Date:  2011-09       Impact factor: 2.375

4.  Patient outcomes associated with group and individual genetic counseling formats.

Authors:  Erin Rothwell; Wendy Kohlmann; Kory Jasperson; Amanda Gammon; Bob Wong; Anita Kinney
Journal:  Fam Cancer       Date:  2012-03       Impact factor: 2.375

5.  Timing of referral for genetic counseling and genetic testing in patients with ovarian, fallopian tube, or primary peritoneal carcinoma.

Authors:  Akiva P Novetsky; Kylie Smith; Sheri A Babb; Donna B Jeffe; Andrea R Hagemann; Premal H Thaker; Matthew A Powell; David G Mutch; L Stewart Massad; Israel Zighelboim
Journal:  Int J Gynecol Cancer       Date:  2013-07       Impact factor: 3.437

6.  The evolution of personalized cancer genetic counseling in the era of personalized medicine.

Authors:  Hetal S Vig; Catharine Wang
Journal:  Fam Cancer       Date:  2012-09       Impact factor: 2.375

7.  Development of a fragile X syndrome (FXS) knowledge scale: towards a modified multidimensional measure of informed choice for FXS population carrier screening.

Authors:  Alice G Ames; Alice Jaques; Obioha C Ukoumunne; Alison D Archibald; Rony E Duncan; Jon Emery; Sylvia A Metcalfe
Journal:  Health Expect       Date:  2012-10-15       Impact factor: 3.377

8.  Development and pilot of an advance care planning website for women with ovarian cancer: a randomized controlled trial.

Authors:  Rachel Isaksson Vogel; Sue V Petzel; Julie Cragg; Molly McClellan; Daniel Chan; Elizabeth Dickson; Julie A Jacko; François Sainfort; Melissa A Geller
Journal:  Gynecol Oncol       Date:  2013-08-27       Impact factor: 5.482

Review 9.  What is lacking in current decision aids on cancer screening?

Authors:  Masahito Jimbo; Gurpreet K Rana; Sarah Hawley; Margaret Holmes-Rovner; Karen Kelly-Blake; Donald E Nease; Mack T Ruffin
Journal:  CA Cancer J Clin       Date:  2013-03-15       Impact factor: 508.702

Review 10.  Genetic counselling and testing for inherited gene mutations in newly diagnosed patients with breast cancer: a review of the existing literature and a proposed research agenda.

Authors:  Bettina Meiser; Kathy Tucker; Michael Friedlander; Kristine Barlow-Stewart; Elizabeth Lobb; Christobel Saunders; Gillian Mitchell
Journal:  Breast Cancer Res       Date:  2008-11-28       Impact factor: 6.466

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