Literature DB >> 18604456

New insights of epithelial-mesenchymal transition in cancer metastasis.

Yadi Wu1, Binhua P Zhou.   

Abstract

Epithelial-mesenchymal transition (EMT) is a key step during embryonic morphogenesis, heart development, chronic degenerative fibrosis, and cancer metastasis. Several distinct traits have been conveyed by EMT, including cell motility, invasiveness, resistance to apoptosis, and some properties of stem cells. Many signal pathways have contributed to the induction of EMT, such as transforming growth factor-beta, Wnt, Hedgehog, Notch, and nuclear factor-kappaB. Over the last few years, increasing evidence has shown that EMT plays an essential role in tumor progression and metastasis. Understanding the molecular mechanism of EMT has a great effect in unraveling the metastatic cascade and may lead to novel interventions for metastatic disease.

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Year:  2008        PMID: 18604456      PMCID: PMC2740620          DOI: 10.1111/j.1745-7270.2008.00443.x

Source DB:  PubMed          Journal:  Acta Biochim Biophys Sin (Shanghai)        ISSN: 1672-9145            Impact factor:   3.848


  97 in total

Review 1.  TGF-beta and epithelial-to-mesenchymal transitions.

Authors:  Jiri Zavadil; Erwin P Böttinger
Journal:  Oncogene       Date:  2005-08-29       Impact factor: 9.867

Review 2.  Carcinoma invasion and metastasis: a role for epithelial-mesenchymal transition?

Authors:  Erik W Thompson; Donald F Newgreen; David Tarin
Journal:  Cancer Res       Date:  2005-07-15       Impact factor: 12.701

Review 3.  The Snail genes as inducers of cell movement and survival: implications in development and cancer.

Authors:  Alejandro Barrallo-Gimeno; M Angela Nieto
Journal:  Development       Date:  2005-07       Impact factor: 6.868

Review 4.  Mammalian cadherins and protocadherins: about cell death, synapses and processing.

Authors:  Dirk Junghans; Ingrid G Haas; Rolf Kemler
Journal:  Curr Opin Cell Biol       Date:  2005-10       Impact factor: 8.382

Review 5.  Molecular requirements for epithelial-mesenchymal transition during tumor progression.

Authors:  Margit A Huber; Norbert Kraut; Hartmut Beug
Journal:  Curr Opin Cell Biol       Date:  2005-10       Impact factor: 8.382

6.  Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer.

Authors:  Tracey A Martin; Amit Goyal; Gareth Watkins; Wen G Jiang
Journal:  Ann Surg Oncol       Date:  2005-04-19       Impact factor: 5.344

7.  Of Snail, mice, and women.

Authors:  Nancy E Davidson; Saraswati Sukumar
Journal:  Cancer Cell       Date:  2005-09       Impact factor: 31.743

Review 8.  The fallacy of epithelial mesenchymal transition in neoplasia.

Authors:  David Tarin; Erik W Thompson; Donald F Newgreen
Journal:  Cancer Res       Date:  2005-07-15       Impact factor: 12.701

9.  Snail, Slug, and Smad-interacting protein 1 as novel parameters of disease aggressiveness in metastatic ovarian and breast carcinoma.

Authors:  Sivan Elloul; Mari Bukholt Elstrand; Jahn M Nesland; Claes G Tropé; Gunnar Kvalheim; Iris Goldberg; Reuven Reich; Ben Davidson
Journal:  Cancer       Date:  2005-04-15       Impact factor: 6.860

Review 10.  Cadherins and catenins in breast cancer.

Authors:  Pamela Cowin; Tracey M Rowlands; Sarah J Hatsell
Journal:  Curr Opin Cell Biol       Date:  2005-10       Impact factor: 8.382

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  92 in total

Review 1.  Cancer stem cells: a novel paradigm for cancer prevention and treatment.

Authors:  Dharmalingam Subramaniam; Satish Ramalingam; Courtney W Houchen; Shrikant Anant
Journal:  Mini Rev Med Chem       Date:  2010-05       Impact factor: 3.862

Review 2.  Estrogen signaling via estrogen receptor {beta}.

Authors:  Chunyan Zhao; Karin Dahlman-Wright; Jan-Åke Gustafsson
Journal:  J Biol Chem       Date:  2010-10-18       Impact factor: 5.157

Review 3.  Autophagy regulation in the development and treatment of breast cancer.

Authors:  Yuting Zhou; Edmund B Rucker; Binhua P Zhou
Journal:  Acta Biochim Biophys Sin (Shanghai)       Date:  2015-12-05       Impact factor: 3.848

Review 4.  VGLL4 is a transcriptional cofactor acting as a novel tumor suppressor via interacting with TEADs.

Authors:  Xiaochong Deng; Lin Fang
Journal:  Am J Cancer Res       Date:  2018-06-01       Impact factor: 6.166

Review 5.  The microRNA networks of TGFβ signaling in cancer.

Authors:  V P Sivadas; S Kannan
Journal:  Tumour Biol       Date:  2013-12-10

6.  Macrophages in skin melanoma-the key element in melanomagenesis.

Authors:  Malgorzata Pieniazek; Rafal Matkowski; Piotr Donizy
Journal:  Oncol Lett       Date:  2018-02-09       Impact factor: 2.967

7.  TGF-β regulation of gene expression at early and late stages of HPV16-mediated transformation of human keratinocytes.

Authors:  Sangeeta Kowli; Rupa Velidandla; Kim E Creek; Lucia Pirisi
Journal:  Virology       Date:  2013-09-19       Impact factor: 3.616

Review 8.  New insights into epithelial-mesenchymal transition in kidney fibrosis.

Authors:  Youhua Liu
Journal:  J Am Soc Nephrol       Date:  2009-12-17       Impact factor: 10.121

9.  Genomic-wide analysis of lymphatic metastasis-associated genes in human hepatocellular carcinoma.

Authors:  Chun Feng Lee; Zhi Qiang Ling; Ting Zhao; Shih Hua Fang; Weng Cheng Chang; San Chih Lee; Kuan Rong Lee
Journal:  World J Gastroenterol       Date:  2009-01-21       Impact factor: 5.742

10.  HOXB9, a gene overexpressed in breast cancer, promotes tumorigenicity and lung metastasis.

Authors:  Tetsu Hayashida; Fumiyuki Takahashi; Naokazu Chiba; Elena Brachtel; Motomi Takahashi; Nadia Godin-Heymann; Kenneth W Gross; Maria d M Vivanco; Vasuki Wijendran; Toshihiro Shioda; Dennis Sgroi; Patricia K Donahoe; Shyamala Maheswaran
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-28       Impact factor: 11.205

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