Literature DB >> 18600424

Generation of planar images from lung ventilation/perfusion SPECT.

Dale L Bailey1, Geoffrey P Schembri, Benjamin E Harris, Elizabeth A Bailey, Robert A Cooper, Paul J Roach.   

Abstract

OBJECTIVE: To develop a method of producing lung ventilation and perfusion (V/Q) planar images using forward projection of reconstructed single-photon emission computed tomography (SPECT) images through approximate attenuation (micro) maps generated from the lung emission scans alone, as transmission-based micro maps may not be routinely available.
METHODS: Synthetic micro maps are derived from (99m)Tc photopeak and "scatter" windows for the attenuation correction of the SPECT images. The attenuation-corrected SPECT images are forward projected at appropriate angles to give the equivalent of planar images. This method allows high-count planar images, as well as the SPECT images, to be produced from a single SPECT acquisition. In addition, isolated "single lung" views of lateral and medial projections without "shine-through" from the contra-lateral lung, which have not been available previously, can be formed.
RESULTS: Comparison of reprojected images produced from CT-derived or synthetic micro maps displayed similar detail and radiopharmaceutical distribution. In a blinded comparison of "true" planar images with those from reprojecting the SPECT data using the synthetic micro maps, no difference in mismatched defect detection was found, and hence it was confirmed that the reprojected planar images could replace true planar images with no loss in planar diagnostic sensitivity.
CONCLUSIONS: The reprojected planar images provide high-count, high-quality images, which are comparable with conventional 2D images.

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Year:  2008        PMID: 18600424     DOI: 10.1007/s12149-007-0120-1

Source DB:  PubMed          Journal:  Ann Nucl Med        ISSN: 0914-7187            Impact factor:   2.668


  3 in total

1.  Attenuation correction for lung SPECT: evidence of need and validation of an attenuation map derived from the emission data.

Authors:  Margarita Núñez; Vineet Prakash; Ricardo Vila; Fernando Mut; Omar Alonso; Brian F Hutton
Journal:  Eur J Nucl Med Mol Imaging       Date:  2009-02-24       Impact factor: 9.236

2.  Joint reconstruction of activity and attenuation map using LM SPECT emission data.

Authors:  Abhinav K Jha; Eric Clarkson; Matthew A Kupinski; Harrison H Barrett
Journal:  Proc SPIE Int Soc Opt Eng       Date:  2013

3.  Thirty years from now: future physics contributions in nuclear medicine.

Authors:  Dale L Bailey
Journal:  EJNMMI Phys       Date:  2014-05-01
  3 in total

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