Literature DB >> 1860012

Raised proinsulin concentration as early indicator of beta cell dysfunction.

D R Williams1, C Byrne, P M Clark, L Cox, N E Day, G Rayman, T Wang, C N Hales.   

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Year:  1991        PMID: 1860012      PMCID: PMC1670642          DOI: 10.1136/bmj.303.6794.95-a

Source DB:  PubMed          Journal:  BMJ        ISSN: 0959-8138


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  1 in total

1.  Sensitive and specific two-site immunoradiometric assays for human insulin, proinsulin, 65-66 split and 32-33 split proinsulins.

Authors:  W J Sobey; S F Beer; C A Carrington; P M Clark; B H Frank; I P Gray; S D Luzio; D R Owens; A E Schneider; K Siddle
Journal:  Biochem J       Date:  1989-06-01       Impact factor: 3.857

  1 in total
  10 in total

1.  Serum proinsulin levels are disproportionately increased in elderly prediabetic subjects.

Authors:  L Mykkänen; S M Haffner; J Kuusisto; K Pyörälä; C N Hales; M Laakso
Journal:  Diabetologia       Date:  1995-10       Impact factor: 10.122

2.  Impaired glucose tolerance and height.

Authors:  D R Williams; P M Clark; N E Day; T Wang; C Byrne; L Cox; C N Hales
Journal:  BMJ       Date:  1991-11-02

3.  Impaired glucose tolerance and height.

Authors:  P M McKeigue
Journal:  BMJ       Date:  1991-08-10

4.  Fasting proinsulin and 2-h post-load glucose levels predict the conversion to NIDDM in subjects with impaired glucose tolerance: the Hoorn Study.

Authors:  G Nijpels; C Popp-Snijders; P J Kostense; L M Bouter; R J Heine
Journal:  Diabetologia       Date:  1996-01       Impact factor: 10.122

5.  Intra-individual variation of glucose, specific insulin and proinsulin concentrations measured by two oral glucose tolerance tests in a general Caucasian population: the Hoorn Study.

Authors:  J M Mooy; P A Grootenhuis; H de Vries; P J Kostense; C Popp-Snijders; L M Bouter; R J Heine
Journal:  Diabetologia       Date:  1996-03       Impact factor: 10.122

Review 6.  Triglycerides and disease.

Authors:  C A Seymour; C D Byrne
Journal:  Postgrad Med J       Date:  1993-09       Impact factor: 2.401

7.  Hypertriglyceridaemia in subjects with normal and abnormal glucose tolerance: relative contributions of insulin secretion, insulin resistance and suppression of plasma non-esterified fatty acids.

Authors:  C D Byrne; N J Wareham; D C Brown; P M Clark; L J Cox; N E Day; C R Palmer; T W Wang; D R Williams; C N Hales
Journal:  Diabetologia       Date:  1994-09       Impact factor: 10.122

8.  Hyperproinsulinaemia in patients with myotonic dystrophy.

Authors:  A J Krentz; P M Clark; L Cox; A C Williams; M Nattrass
Journal:  Diabetologia       Date:  1992-12       Impact factor: 10.122

9.  Effects of octreotide on circulating islet B cell products in endogenous hyperinsulinism.

Authors:  A J Krentz; J Pace; W Somerville; P M Clark; M Nattrass
Journal:  Postgrad Med J       Date:  1993-09       Impact factor: 2.401

10.  Hyperproinsulinemia is associated with increased beta cell demand after hemipancreatectomy in humans.

Authors:  E R Seaquist; S E Kahn; P M Clark; C N Hales; D Porte; R P Robertson
Journal:  J Clin Invest       Date:  1996-01-15       Impact factor: 14.808

  10 in total

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