Literature DB >> 18599358

High-dose-rate brachytherapy in a large squamous cell carcinoma of the hand.

Maria Grazia Fabrini1, Franco Perrone, Mario De Liguoro, Luca Cionini.   

Abstract

PURPOSE: High-dose-rate (192)Ir-based brachytherapy can be used as an exclusive treatment of large skin tumors when teletherapy or surgery is not feasible. A case of an extended inoperable skin epithelioma of the hand is reported; the lesion involved the first finger, the tenar, the palm, and the back. METHODS AND MATERIALS: A detailed description of an individual case is reported. A customized mold was created for the patient, to administer a fractionated brachytherapy treatment in a reproducible way.
RESULTS: A total dose of 50Gy was administered in 10 fractions, after a time schedule of three fractions per week. The treatment was well tolerated and the acute effects (mainly, epitheliolysis) were resolved completely within a month after the treatment.
CONCLUSIONS: Nine months after the treatment, the malignant lesion completely disappeared and the cosmetic results are quite satisfactory. Therefore, we conclude that the treatment technique is well adaptable to any particular geometry and that the fractionation scheme has proven to be well tolerated and effective in tumor eradication.

Entities:  

Mesh:

Year:  2008        PMID: 18599358     DOI: 10.1016/j.brachy.2008.04.004

Source DB:  PubMed          Journal:  Brachytherapy        ISSN: 1538-4721            Impact factor:   2.362


  7 in total

1.  Externally applied high-dose-rate brachytherapy for deeply invasive cutaneous squamous cell carcinoma in an older patient.

Authors:  Melodi Javid Whitley; Adela R Cardones; Oana I Craciunescu; David G Kirsch
Journal:  Pract Radiat Oncol       Date:  2015-11-17

Review 2.  Clinical implementation of a new electronic brachytherapy system for skin brachytherapy.

Authors:  Olga Pons-Llanas; Rosa Ballester-Sánchez; Francisco Javier Celada-Álvarez; Cristian Candela-Juan; Teresa García-Martínez; Margarita Llavador-Ros; Rafael Botella-Estrada; Christopher A Barker; Antonio Ballesta; Alejandro Tormo-Micó; Silvia Rodríguez; Jose Perez-Calatayud
Journal:  J Contemp Brachytherapy       Date:  2014-12-31

3.  Electronic brachytherapy for superficial and nodular basal cell carcinoma: a report of two prospective pilot trials using different doses.

Authors:  Rosa Ballester-Sánchez; Olga Pons-Llanas; Cristian Candela-Juan; Francisco Javier Celada-Álvarez; Christopher A Barker; Alejandro Tormo-Micó; Jose Pérez-Calatayud; Rafael Botella-Estrada
Journal:  J Contemp Brachytherapy       Date:  2016-01-28

Review 4.  Non-melanoma skin cancer treated with high-dose-rate brachytherapy: a review of literature.

Authors:  Durim Delishaj; Agata Rembielak; Bruno Manfredi; Stefano Ursino; Francesco Pasqualetti; Concetta Laliscia; Francesca Orlandi; Riccardo Morganti; Maria Grazia Fabrini; Fabiola Paiar
Journal:  J Contemp Brachytherapy       Date:  2016-12-02

5.  Non-melanoma skin cancer treated with HDR Valencia applicator: clinical outcomes.

Authors:  Alejandro Tormo; Francisco Celada; Silvia Rodriguez; Rafael Botella; Antonio Ballesta; Michael Kasper; Zoubir Ouhib; Manuel Santos; Jose Perez-Calatayud
Journal:  J Contemp Brachytherapy       Date:  2014-06-03

6.  Non-melanoma skin cancer treated with high-dose-rate brachytherapy and Valencia applicator in elderly patients: a retrospective case series.

Authors:  Durim Delishaj; Concetta Laliscia; Bruno Manfredi; Stefano Ursino; Francesco Pasqualetti; Ezio Lombardo; Franco Perrone; Riccardo Morganti; Fabiola Paiar; Maria Grazia Fabrini
Journal:  J Contemp Brachytherapy       Date:  2015-11-23

7.  Long-term remission after low dose radiotherapy in patient with extensive squamous cell carcinoma of the hand: A case report.

Authors:  Timothy Cheo; Ivy Ng; Kiat Huat Ooi; Bok Ai Choo
Journal:  Medicine (Baltimore)       Date:  2016-09       Impact factor: 1.889

  7 in total

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