BACKGROUND: Although the prevalence of dementia increases with age from ages 65 to 85, whether this increase continues after age 90 is unclear. Most studies reporting on dementia prevalence do not have sufficient participants to estimate prevalence for specific ages and sexes above age 90. Here, we estimate age- and sex-specific prevalence of all-cause dementia in the oldest-old, those aged 90 and older. METHODS: Participants are 911 elderly from The 90+ Study, a population-based study of aging and dementia in people aged 90 and above. Dementia was diagnosed using in-person examinations as well as telephone and informant questionnaires. RESULTS: The overall prevalence of all-cause dementia was higher in women (45%, 95% CI = 41.5-49.0) than men (28%, 95% CI = 21.7-34.2). Among women, prevalence increased with age after age 90, essentially doubling every 5 years. A lower prevalence of dementia was significantly associated with higher education in women but not in men. CONCLUSIONS: In a very large sample of participants aged 90 and older, prevalence of all-cause dementia doubled every 5 years for women but not men.
BACKGROUND: Although the prevalence of dementia increases with age from ages 65 to 85, whether this increase continues after age 90 is unclear. Most studies reporting on dementia prevalence do not have sufficient participants to estimate prevalence for specific ages and sexes above age 90. Here, we estimate age- and sex-specific prevalence of all-cause dementia in the oldest-old, those aged 90 and older. METHODS:Participants are 911 elderly from The 90+ Study, a population-based study of aging and dementia in people aged 90 and above. Dementia was diagnosed using in-person examinations as well as telephone and informant questionnaires. RESULTS: The overall prevalence of all-cause dementia was higher in women (45%, 95% CI = 41.5-49.0) than men (28%, 95% CI = 21.7-34.2). Among women, prevalence increased with age after age 90, essentially doubling every 5 years. A lower prevalence of dementia was significantly associated with higher education in women but not in men. CONCLUSIONS: In a very large sample of participants aged 90 and older, prevalence of all-cause dementia doubled every 5 years for women but not men.
Authors: Kewei Chen; Napatkamon Ayutyanont; Jessica B S Langbaum; Adam S Fleisher; Cole Reschke; Wendy Lee; Xiaofen Liu; Dan Bandy; Gene E Alexander; Paul M Thompson; Leslie Shaw; John Q Trojanowski; Clifford R Jack; Susan M Landau; Norman L Foster; Danielle J Harvey; Michael W Weiner; Robert A Koeppe; William J Jagust; Eric M Reiman Journal: Neuroimage Date: 2011-01-27 Impact factor: 6.556
Authors: Leonard W Poon; John L Woodard; L Stephen Miller; Robert Green; Marla Gearing; Adam Davey; Jonathan Arnold; Peter Martin; Ilene C Siegler; Lusine Nahapetyan; Young Sek Kim; William Markesbery Journal: J Gerontol A Biol Sci Med Sci Date: 2012-03-01 Impact factor: 6.053
Authors: Adina Zeki Al Hazzouri; Eric Vittinghoff; Amy Byers; Ken Covinsky; Dan Blazer; Susan Diem; Kristine E Ensrud; Kristine Yaffe Journal: J Gerontol A Biol Sci Med Sci Date: 2013-10-04 Impact factor: 6.053