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Literature DB >> 185954

Therapeutic effects of small-particle aerosols of ribavirin on parainfluenza (sendai) virus infections of mice.

Abstract

Small-particle aerosol administration of ribavirin (1-beta-d-ribofuranosyl-1,2,4-triazole-3-carboxamide) increased survival rates, extended the time to death, delayed lung pathology, and reduced pulmonary virus levels in Sendai virus-infected mice.

Entities: Chemical Disease Species

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Year: 1976 PMID： 185954 PMCID： PMC429828 DOI： 10.1128/AAC.10.4.770

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

10 in total

1. Small-particle aerosols of antiviral compounds in treatment of type A influenza pneumonia in mice.

Authors: J S Walker; E L Stephen; R O Spertzel
Journal: J Infect Dis Date: 1976-06 Impact factor: 5.226

2. Pathogenesis of Sendai virus infection in mice.

Authors: L H Appell; R M Kovatch; J M Reddecliff; P J Gerone
Journal: Am J Vet Res Date: 1971-11 Impact factor: 1.156

3. Sendai virus infection of rats as a convenient model of acute respiratory infection.

Authors: D A Tyrrell; C R Coid
Journal: Vet Rec Date: 1970-02-07 Impact factor: 2.695

4. Experimental infection with Sendai virus in mice.

Authors: M C van Nunen; J van der Veen
Journal: Arch Gesamte Virusforsch Date: 1967

5. The pathogenesis of Sendai virus infection in the mouse lung.

Authors: T W Robinson; R J Cureton; R B Heath
Journal: J Med Microbiol Date: 1968-08 Impact factor: 2.472

6. Natural history of Sendai virus infection in mice.

Authors: J C Parker; R K Reynolds
Journal: Am J Epidemiol Date: 1968-07 Impact factor: 4.897

7. Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide.

Authors: R W Sidwell; J H Huffman; G P Khare; L B Allen; J T Witkowski; R K Robins
Journal: Science Date: 1972-08-25 Impact factor: 47.728

8. Synergistic effect in viral-bacterial infection: combined infection of the murine respiratory tract with Sendai virus and Pasteurella pneumotropica.

Authors: G J Jakab; E C Dick
Journal: Infect Immun Date: 1973-11 Impact factor: 3.441

9. In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses.

Authors: J H Huffman; R W Sidwell; G P Khare; J T Witkowski; L B Allen; R K Robins
Journal: Antimicrob Agents Chemother Date: 1973-02 Impact factor: 5.191

10. Treatment of influenza infection of mice by using rimantadine hydrochlorides by the aerosol and intraperitoneal routes.

Authors: E L Stephen; J W Dominik; J B Moe; R O Spertzel; J S Walker
Journal: Antimicrob Agents Chemother Date: 1975-08 Impact factor: 5.191

10 in total

6 in total

Therapeutic effects of small-particle aerosols of ribavirin on parainfluenza (sendai) virus infections of mice.

1. Small-particle aerosols of antiviral compounds in treatment of type A influenza pneumonia in mice.

2. Pathogenesis of Sendai virus infection in mice.

3. Sendai virus infection of rats as a convenient model of acute respiratory infection.

4. Experimental infection with Sendai virus in mice.

5. The pathogenesis of Sendai virus infection in the mouse lung.

6. Natural history of Sendai virus infection in mice.

7. Broad-spectrum antiviral activity of Virazole: 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide.

8. Synergistic effect in viral-bacterial infection: combined infection of the murine respiratory tract with Sendai virus and Pasteurella pneumotropica.

9. In vitro effect of 1-beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide (virazole, ICN 1229) on deoxyribonucleic acid and ribonucleic acid viruses.

10. Treatment of influenza infection of mice by using rimantadine hydrochlorides by the aerosol and intraperitoneal routes.

Review 1. Biochemistry and clinical applications of ribavirin.

2. Cell type mediated resistance of vesicular stomatitis virus and Sendai virus to ribavirin.

Review 3. Ribavirin and inosiplex: a review of their present status in viral diseases.

4. Sensitive radioimmunoassay for the broad-spectrum antiviral agent ribavirin.

5. Inhibition of lymphocyte proliferative responses by ribavirin.

Review 6. Antiviral therapy for respiratory tract infections.