| Literature DB >> 18593872 |
Hye Ryun Woo1, Eric J Richards.
Abstract
Among the persistent mysteries in epigenetics are the criteria by which specific regions of the genome are chosen for deposition of distinguishing chromatin marks. Once a particular region is modified, will the newly acquired epigenetic state spill onto neighboring regions of the genome or be confined to tidy patches? The report by Henderson and Jacobsen in the the previous issue of Genes & Development (1597-1606) addresses these questions while providing insight into the utility of DNA methylation for a eukaryotic genome.Entities:
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Year: 2008 PMID: 18593872 PMCID: PMC2732421 DOI: 10.1101/gad.1694608
Source DB: PubMed Journal: Genes Dev ISSN: 0890-9369 Impact factor: 11.361