Literature DB >> 18591270

Role of plasma proteins in pharmacokinetics of micafungin, an antifungal antibiotic, in analbuminemic rats.

Fumie Abe1, Jun Ueyama, Noriyo Kawasumi, Masayuki Nadai, Tamon Hayashi, Miki Kato, Masafumi Ohnishi, Hiroko Saito, Naoshi Takeyama, Takaaki Hasegawa.   

Abstract

There were no significant differences in the pharmacokinetics of micafungin and expression of hepatic multidrug resistance-associated protein 2 (ABCC2/Mrp2) between analbuminemic and Sprague-Dawley rats. Micafungin bound strongly to high-density lipoprotein (HDL) and moderately to gamma globulin. These results suggest that HDL and gamma globulin contribute to the pharmacokinetics of micafungin.

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Year:  2008        PMID： 18591270      PMCID： PMC2533450          DOI： 10.1128/AAC.00396-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  16 in total

1.  Pharmacokinetic behavior of micafungin in rats with carbon tetrachloride-induced acute hepatic failure.

Authors:  Hiroki Konishi; Masatomo Sudo; Masaki Sumi; Hiroaki Morii; Tokuzo Minouchi; Tachio Aimoto; Akira Yamaji
Journal:  Biol Pharm Bull       Date:  2005-03       Impact factor: 2.233

2.  Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs.

Authors:  Toshiyuki Sakaeda; Koichi Iwaki; Mikio Kakumoto; Mika Nishikawa; Toshiro Niwa; Jiang-shu Jin; Tsutomu Nakamura; Kohshi Nishiguchi; Noboru Okamura; Katsuhiko Okumura
Journal:  J Pharm Pharmacol       Date:  2005-06       Impact factor: 3.765

3.  Pharmacokinetics of oltipraz in mutant Nagase analbuminemic rats.

Authors:  Soo K Bae; Hee E Kang; Min K Kang; Jin W Kim; Taekrho Kim; Myung G Lee
Journal:  J Pharm Sci       Date:  2006-05       Impact factor: 3.534

4.  Effects of hepatic CYP3A4 activity on disposition of micafungin in liver transplant recipients with markedly small-for-size grafts.

Authors:  N Mochizuki; K Matsumoto; K Ohno; T Shimamura; H Furukawa; S Todo; S Kishino
Journal:  Transplant Proc       Date:  2006-12       Impact factor: 1.066

5.  Pharmacokinetics of cisplatin in analbuminemic rats.

Authors:  K Takada; T Kawamura; M Inai; S Masuda; T Oka; Y Yoshikawa; N Shibata; H Yoshikawa; O Ike; H Wada; S Hitomi
Journal:  Biopharm Drug Dispos       Date:  1999-12       Impact factor: 1.627

6.  Albumin-deficient rat mutant.

Authors:  S Nagase; K Shimamune; S Shumiya
Journal:  Science       Date:  1979-08-10       Impact factor: 47.728

7.  Pharmacokinetics of intravenous theophylline in mutant Nagase analbuminemic rats.

Authors:  Eun Jung Kim; Ok Kyung Suh; Myung Gull Lee
Journal:  Life Sci       Date:  2003-01-31       Impact factor: 5.037

8.  Pharmacokinetics and pharmacodynamics of intravenous trasemide in mutant Nagase analbuminemic rats.

Authors:  Eun J Kim; Myung G Lee
Journal:  Biopharm Drug Dispos       Date:  2003-01       Impact factor: 1.627

9.  Involvement of multidrug resistance-associated protein 2 (ABCC2/Mrp2) in biliary excretion of micafungin in rats.

Authors:  Fumie Abe; Jun Ueyama; Akiko Kimata; Miki Kato; Tamon Hayashi; Masayuki Nadai; Hiroko Saito; Naoshi Takeyama; Hiroshi Noguchi; Takaaki Hasegawa
Journal:  Life Sci       Date:  2008-07-01       Impact factor: 5.037

10.  Pharmacokinetics and pharmacodynamics of intravenous azosemide in mutant Nagase analbuminemic rats.

Authors:  Eun J Kim; Ae K Lee; So H Kim; Sang G Kim; Myung G Lee
Journal:  Drug Metab Dispos       Date:  2003-02       Impact factor: 3.922
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  6 in total

1.  Bronchopulmonary disposition of micafungin in healthy adult volunteers.

Authors:  Anthony M Nicasio; Pamela R Tessier; David P Nicolau; R Fredrick Knauft; John Russomanno; Eric Shore; Joseph L Kuti
Journal:  Antimicrob Agents Chemother       Date:  2008-12-29       Impact factor: 5.191

2.  Intrapulmonary pharmacokinetics and pharmacodynamics of micafungin in adult lung transplant patients.

Authors:  Thomas J Walsh; Sylvain Goutelle; Roger W Jelliffe; Jeffrey A Golden; Emily A Little; Catherine DeVoe; Diana Mickiene; Maggie Hayes; John E Conte
Journal:  Antimicrob Agents Chemother       Date:  2010-05-03       Impact factor: 5.191

3.  Higher clearance of micafungin in neonates compared with adults: role of age-dependent micafungin serum binding.

Authors:  Souzan B Yanni; P Brian Smith; Daniel K Benjamin; Patrick F Augustijns; Dhiren R Thakker; Pieter P Annaert
Journal:  Biopharm Drug Dispos       Date:  2011-03-30       Impact factor: 1.627

4.  Effect of blood decrease on micafungin disposition in rats.

Authors:  Hiroki Konishi; Keizo Fukushima; Masatomo Sudo; Masaki Sumi; Tokuzo Minouchi; Ikumi Iga; Nobuhito Shibata; Akira Yamaji
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2011-02-25       Impact factor: 2.441

5.  Improved detection of Candida sp. fks hot spot mutants by using the method of the CLSI M27-A3 document with the addition of bovine serum albumin.

Authors:  Guillermo Garcia-Effron; Steven Park; David S Perlin
Journal:  Antimicrob Agents Chemother       Date:  2011-03-07       Impact factor: 5.191

6.  In vitro investigation of the hepatobiliary disposition mechanisms of the antifungal agent micafungin in humans and rats.

Authors:  Souzan B Yanni; Patrick F Augustijns; Daniel K Benjamin; Kim L R Brouwer; Dhiren R Thakker; Pieter P Annaert
Journal:  Drug Metab Dispos       Date:  2010-07-06       Impact factor: 3.922
  6 in total

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