Literature DB >> 18587411

Architects of assembly: roles of Flaviviridae non-structural proteins in virion morphogenesis.

Catherine L Murray1, Christopher T Jones, Charles M Rice.   

Abstract

Viruses of the Flaviviridae family, including hepatitis C, dengue and bovine viral diarrhoea, are responsible for considerable morbidity and mortality worldwide. Recent advances in our understanding of virion assembly have uncovered commonalities among distantly related members of this family. We discuss the emerging hypothesis that physical virion components are not alone in forming the infectious particle, but that non-structural proteins are intimately involved in orchestrating morphogenesis. Pinpointing the roles of Flaviviridae proteins in virion production could reveal new avenues for antiviral therapeutics.

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Year:  2008        PMID： 18587411      PMCID： PMC2764292          DOI： 10.1038/nrmicro1928

Source DB:  PubMed          Journal:  Nat Rev Microbiol        ISSN： 1740-1526            Impact factor:   60.633


  108 in total

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3.  Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution.

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Journal:  J Virol       Date:  2007-02-14       Impact factor: 5.103

4.  Structure of immature West Nile virus.

Authors:  Ying Zhang; Bärbel Kaufmann; Paul R Chipman; Richard J Kuhn; Michael G Rossmann
Journal:  J Virol       Date:  2007-03-21       Impact factor: 5.103

5.  Hepatitis C virus production by human hepatocytes dependent on assembly and secretion of very low-density lipoproteins.

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6.  Compensatory mutations in E1, p7, NS2, and NS3 enhance yields of cell culture-infectious intergenotypic chimeric hepatitis C virus.

Authors:  MinKyung Yi; Yinghong Ma; Jeremy Yates; Stanley M Lemon
Journal:  J Virol       Date:  2006-11-01       Impact factor: 5.103

7.  Association between NS3 and NS5 proteins of dengue virus type 2 in the putative RNA replicase is linked to differential phosphorylation of NS5.

Authors:  M Kapoor; L Zhang; M Ramachandra; J Kusukawa; K E Ebner; R Padmanabhan
Journal:  J Biol Chem       Date:  1995-08-11       Impact factor: 5.157

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Authors:  K Elbers; N Tautz; P Becher; D Stoll; T Rümenapf; H J Thiel
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

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Journal:  J Virol       Date:  1995-12       Impact factor: 5.103

10.  Hepatitis C virus NS5A is a direct substrate of casein kinase I-alpha, a cellular kinase identified by inhibitor affinity chromatography using specific NS5A hyperphosphorylation inhibitors.

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  99 in total

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2.  Crystal structure of a novel conformational state of the flavivirus NS3 protein: implications for polyprotein processing and viral replication.

Authors:  René Assenberg; Eloise Mastrangelo; Thomas S Walter; Anil Verma; Mario Milani; Raymond J Owens; David I Stuart; Jonathan M Grimes; Erika J Mancini
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Authors:  Tung Phan; Rudolf K F Beran; Christopher Peters; Ivo C Lorenz; Brett D Lindenbach
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Review 4.  Therapeutic Approaches for Zika Virus Infection of the Nervous System.

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Journal:  Neurotherapeutics       Date:  2017-10       Impact factor: 7.620

Review 5.  Advances and controversies in yellow fever vaccination.

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6.  Mechanisms of HCV NS3 helicase monitored by optical tweezers.

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Journal:  Methods Mol Biol       Date:  2015

7.  Japanese encephalitis virus core protein inhibits stress granule formation through an interaction with Caprin-1 and facilitates viral propagation.

Authors:  Hiroshi Katoh; Toru Okamoto; Takasuke Fukuhara; Hiroto Kambara; Eiji Morita; Yoshio Mori; Wataru Kamitani; Yoshiharu Matsuura
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8.  MicroRNA-like viral small RNA from Dengue virus 2 autoregulates its replication in mosquito cells.

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9.  Degradation of MicroRNA miR-466d-3p by Japanese Encephalitis Virus NS3 Facilitates Viral Replication and Interleukin-1β Expression.

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Review 10.  Towards a small animal model for hepatitis C.

Authors:  Alexander Ploss; Charles M Rice
Journal:  EMBO Rep       Date:  2009-10-16       Impact factor: 8.807
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