Literature DB >> 18582437

Post-transcriptional control of gene expression through subcellular relocalization of mRNA binding proteins.

Anne Cammas1, Stephen M Lewis, Stephan Vagner, Martin Holcik.   

Abstract

Eukaryotic cells have developed multiple mechanisms to respond to different physiological cues, such as cellular stress, which allow the cells to adapt themselves to their new environment. The regulation of post-transcriptional gene expression is an important component of the cellular stress response and is mediated by mRNA binding proteins (mRBPs). Recently, several studies have shown that regulated subcellular localization of mRBPs upon diverse stimuli (such as cellular stress) provides an additional level of regulation for gene expression.

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Year:  2008        PMID: 18582437     DOI: 10.1016/j.bcp.2008.05.022

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


  12 in total

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